Молекулярна функція | • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • sequence-specific DNA binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding • transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • p53 binding • DNA binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific |
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Біологічний процес | • anterior/posterior pattern specification • negative regulation of cell population proliferation • negative regulation of striated muscle cell differentiation • signal transduction involved in regulation of gene expression • regulation of odontogenesis • negative regulation of transcription regulatory region DNA binding • stem cell differentiation • positive regulation of mesenchymal cell apoptotic process • mammary gland epithelium development • negative regulation of apoptotic process • activation of meiosis • positive regulation of BMP signaling pathway • transcription, DNA-templated • cartilage morphogenesis • positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator • multicellular organism development • odontogenesis • bone morphogenesis • embryonic limb morphogenesis • BMP signaling pathway • middle ear morphogenesis • mesenchymal cell proliferation • embryonic forelimb morphogenesis • negative regulation of DNA binding • positive regulation of DNA damage response, signal transduction by p53 class mediator • heart morphogenesis • BMP signaling pathway involved in heart development • GO:0000767 cell morphogenesis • heart development • forebrain development • muscle organ development • GO:1901227 negative regulation of transcription by RNA polymerase II • roof of mouth development • embryonic digit morphogenesis • in utero embryonic development • protein stabilization • GO:0009373 regulation of transcription, DNA-templated • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • epithelial to mesenchymal transition involved in endocardial cushion formation • transcription by RNA polymerase II • negative regulation of cell growth • Епітеліально-мезенхімальний перехід • embryonic hindlimb morphogenesis • GO:0045996 negative regulation of transcription, DNA-templated • protein localization to nucleus • midbrain development • odontogenesis of dentin-containing tooth • embryonic nail plate morphogenesis • face morphogenesis • pituitary gland development • cellular response to nicotine • cartilage development • embryonic morphogenesis |
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