CEBPB |
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Наявні структури |
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PDB | Пошук ортологів: PDBe RCSB | Список кодів PDB | 1GTW, 1GU4, 1GU5, 1H88, 1H89, 1H8A, 1HJB, 1IO4, 2E42, 2E43 | | |
Ідентифікатори |
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Символи | CEBPB, C/EBP-beta, IL6DBP, NF-IL6, TCF5, CCAAT/enhancer binding protein beta, CCAAT enhancer binding protein beta |
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Зовнішні ІД | OMIM: 189965 MGI: 88373 HomoloGene: 3807 GeneCards: CEBPB |
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Онтологія гена |
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Молекулярна функція | • DNA binding • sequence-specific DNA binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding • protein homodimerization activity • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • transcription factor binding • histone deacetylase binding • chromatin binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • kinase binding • GO:0001948, GO:0016582 protein binding • histone acetyltransferase binding • ubiquitin-like protein ligase binding • protein heterodimerization activity • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding • RNA polymerase II core promoter sequence-specific DNA binding • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • glucocorticoid receptor binding |
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Клітинна компонента | • цитоплазма • nuclear matrix • CHOP-C/EBP complex • нуклеоплазма • клітинне ядро • condensed chromosome, centromeric region • RNA polymerase II transcription regulator complex |
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Біологічний процес | • GO:1904089 negative regulation of neuron apoptotic process • mammary gland epithelial cell proliferation • диференціація клітин • GO:0009373 regulation of transcription, DNA-templated • positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress • GO:1904579 cellular response to organic cyclic compound • embryonic placenta development • пам'ять • positive regulation of interleukin-4 production • response to endoplasmic reticulum stress • mammary gland epithelial cell differentiation • transcription, DNA-templated • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • negative regulation of T cell proliferation • liver regeneration • positive regulation of osteoblast differentiation • hepatocyte proliferation • response to lipopolysaccharide • regulation of osteoclast differentiation • defense response to bacterium • acute-phase response • GO:0046730, GO:0046737, GO:0046738, GO:0046736 імунна відповідь • neuron differentiation • cellular response to interleukin-1 • brown fat cell differentiation • cellular response to amino acid stimulus • ovarian follicle development • liver development • inflammatory response • GO:0045996 negative regulation of transcription, DNA-templated • positive regulation of fat cell differentiation • cellular response to lipopolysaccharide • fat cell differentiation • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress • transcription by RNA polymerase II • granuloma formation • T-helper 1 cell activation • GO:1901227 negative regulation of transcription by RNA polymerase II • regulation of odontoblast differentiation • positive regulation of biomineral tissue development • positive regulation of sodium-dependent phosphate transport • positive regulation of inflammatory response • positive regulation of cold-induced thermogenesis • regulation of dendritic cell differentiation |
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Джерела:Amigo / QuickGO | |
Шаблон експресії |
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Більше даних |
Ортологи |
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Види | Людина | Миша |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (мРНК) | | NM_005194 NM_001285878 NM_001285879 |
| | NM_001287738 NM_001287739 NM_009883 |
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RefSeq (білок) | | NP_001272807 NP_001272808 NP_005185 |
| | NP_001274667 NP_001274668 NP_034013 |
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Локус (UCSC) | Хр. 20: 50.19 – 50.19 Mb | Хр. 2: 167.53 – 167.53 Mb |
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PubMed search | [1] | [2] |
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Вікідані |
Див./Ред. для людей | Див./Ред. для мишей |
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