BCL10 |
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Наявні структури |
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PDB | Пошук ортологів: PDBe RCSB | | |
Ідентифікатори |
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Символи | BCL10, CARMEN, CIPER, CLAP, c-E10, mE10, IMD37, B-cell CLL/lymphoma 10, B cell CLL/lymphoma 10, immune signaling adaptor, BCL10 immune signaling adaptor |
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Зовнішні ІД | OMIM: 603517 MGI: 1337994 HomoloGene: 2912 GeneCards: BCL10 |
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Пов'язані генетичні захворювання |
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MALT lymphoma[1] |
Онтологія гена |
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Молекулярна функція | • GO:0001105 transcription coactivator activity • transcription factor binding • protein kinase B binding • NF-kappaB binding • protease binding • protein self-association • kinase binding • protein C-terminus binding • GO:0001948, GO:0016582 protein binding • kinase activator activity • enzyme binding • protein kinase binding • ubiquitin protein ligase binding • identical protein binding • CARD domain binding |
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Клітинна компонента | • цитоплазма • гіалоплазма • мембрана • T cell receptor complex • lipopolysaccharide receptor complex • immunological synapse • perinuclear region of cytoplasm • membrane raft • cytoplasmic microtubule • лізосома • клітинне ядро • CBM complex • GO:0009327 protein-containing complex |
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Біологічний процес | • GO:0097285 апоптоз • T cell apoptotic process • regulation of apoptotic process • адаптивна імунна відповідь • B cell apoptotic process • regulation of T cell receptor signaling pathway • процес імунної системи • смерть клітини • stimulatory C-type lectin receptor signaling pathway • negative regulation of mature B cell apoptotic process • toll-like receptor signaling pathway • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • Fc-epsilon receptor signaling pathway • cellular defense response • positive regulation of cysteine-type endopeptidase activity involved in apoptotic process • cellular response to mechanical stimulus • neural tube closure • response to fungus • positive regulation of T cell activation • positive regulation of NF-kappaB transcription factor activity • immunoglobulin mediated immune response • protein complex oligomerization • positive regulation of mast cell cytokine production • response to food • positive regulation of I-kappaB kinase/NF-kappaB signaling • positive regulation of extrinsic apoptotic signaling pathway • positive regulation of phosphorylation • response to molecule of bacterial origin • I-kappaB kinase/NF-kappaB signaling • positive regulation of protein ubiquitination • T cell receptor signaling pathway • protein homooligomerization • вроджений імунітет • Убіквітин-залежний протеоліз • positive regulation of apoptotic process • protein heterooligomerization • lipopolysaccharide-mediated signaling pathway • positive regulation of kinase activity |
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Джерела:Amigo / QuickGO | |
Ортологи |
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Види | Людина | Миша |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (мРНК) | | |
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RefSeq (білок) | | NP_001307644 NP_003912 NP_001307644.1 |
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Локус (UCSC) | Хр. 1: 85.27 – 85.28 Mb | Хр. 3: 145.63 – 145.64 Mb |
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PubMed search | [2] | [3] |
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Вікідані |
Див./Ред. для людей | Див./Ред. для мишей |
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