TNFRSF1B |
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Наявні структури |
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PDB | Пошук ортологів: PDBe RCSB | Список кодів PDB | 1CA9, 3ALQ | | |
Ідентифікатори |
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Символи | TNFRSF1B, CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR, tumor necrosis factor receptor superfamily member 1B, TNF receptor superfamily member 1B |
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Зовнішні ІД | OMIM: 191191 MGI: 1314883 HomoloGene: 829 GeneCards: TNFRSF1B |
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Онтологія гена |
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Молекулярна функція | • GO:0001948, GO:0016582 protein binding • ubiquitin protein ligase binding • tumor necrosis factor-activated receptor activity • tumor necrosis factor binding |
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Клітинна компонента | • integral component of membrane • мембрана • клітинна мембрана • integral component of plasma membrane • varicosity • extracellular region • аксон • neuronal cell body • perinuclear region of cytoplasm • membrane raft • клітинне ядро • specific granule membrane • tumor necrosis factor receptor superfamily complex |
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Біологічний процес | • extrinsic apoptotic signaling pathway • RNA destabilization • cellular response to growth factor stimulus • positive regulation of membrane protein ectodomain proteolysis • GO:0010260 старіння людини • multicellular organism development • cell surface receptor signaling pathway • response to lipopolysaccharide • regulation of cell population proliferation • GO:0046730, GO:0046737, GO:0046738, GO:0046736 імунна відповідь • intrinsic apoptotic signaling pathway in response to DNA damage • apoptotic signaling pathway • inflammatory response • cellular response to lipopolysaccharide • negative regulation of inflammatory response • GO:0097285 апоптоз • tumor necrosis factor-mediated signaling pathway • neutrophil degranulation • negative regulation of cysteine-type endopeptidase activity involved in apoptotic process • cytokine-mediated signaling pathway • aortic valve development • pulmonary valve development • negative regulation of extracellular matrix constituent secretion • negative regulation of cardiac muscle hypertrophy • positive regulation of apoptotic process involved in morphogenesis • regulation of T cell cytokine production • regulation of myelination • regulation of T cell proliferation • regulation of neuroinflammatory response • cellular response to tumor necrosis factor • positive regulation of myelination • positive regulation of oligodendrocyte differentiation • negative regulation of cell death • negative regulation of neuroinflammatory response • glial cell-neuron signaling • negative regulation of neuron death • regulation of RNA biosynthetic process |
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Джерела:Amigo / QuickGO | |
Шаблон експресії |
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Більше даних |
Ортологи |
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Види | Людина | Миша |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (мРНК) | | |
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RefSeq (білок) | | |
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Локус (UCSC) | Хр. 1: 12.17 – 12.21 Mb | Хр. 4: 144.94 – 144.97 Mb |
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PubMed search | [1] | [2] |
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Вікідані |
Див./Ред. для людей | Див./Ред. для мишей |
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