CD44 |
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Наявні структури |
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PDB | Пошук ортологів: PDBe RCSB | Список кодів PDB | 1POZ, 1UUH, 2I83, 4PZ3, 4PZ4 | | |
Ідентифікатори |
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Символи | CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CD44 molecule (Indian blood group) |
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Зовнішні ІД | OMIM: 107269 MGI: 88338 HomoloGene: 508 GeneCards: CD44 |
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Онтологія гена |
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Молекулярна функція | • collagen binding • GO:0001948, GO:0016582 protein binding • hyaluronic acid binding • GO:0016518 cytokine receptor activity • transmembrane signaling receptor activity |
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Клітинна компонента | • integral component of membrane • комплекс Ґольджі • macrophage migration inhibitory factor receptor complex • мембрана • focal adhesion • клітинна мембрана • integral component of plasma membrane • cell surface • екзосома • гіалоплазма • secretory granule membrane • apical plasma membrane • lamellipodium membrane • cell projection • Мікроворсинки • basolateral plasma membrane |
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Біологічний процес | • negative regulation of cysteine-type endopeptidase activity involved in apoptotic process • monocyte aggregation • positive regulation of heterotypic cell-cell adhesion • hyaluronan catabolic process • negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator • interferon-gamma-mediated signaling pathway • extracellular matrix disassembly • extracellular matrix organization • negative regulation of apoptotic process • cellular response to fibroblast growth factor stimulus • positive regulation of peptidyl-serine phosphorylation • cartilage development • адгезія клітин • negative regulation of DNA damage response, signal transduction by p53 class mediator • positive regulation of ERK1 and ERK2 cascade • positive regulation of peptidyl-tyrosine phosphorylation • cell-matrix adhesion • positive regulation of monocyte aggregation • leukocyte migration • neutrophil degranulation • wound healing, spreading of cells • regulation of lamellipodium morphogenesis • cell-cell adhesion • inflammatory response • cell migration • T cell activation • positive regulation of kinase activity |
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Джерела:Amigo / QuickGO | |
Шаблон експресії |
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Більше даних |
Ортологи |
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Види | Людина | Миша |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (мРНК) | NM_000610 NM_001001389 NM_001001390 NM_001001391 NM_001001392
| NM_001202555 NM_001202556 NM_001202557 |
| NM_001039150 NM_001039151 NM_001177785 NM_001177786 NM_001177787
| NM_009851 |
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RefSeq (білок) | NP_000601 NP_001001389 NP_001001390 NP_001001391 NP_001001392
| NP_001189484 NP_001189485 NP_001189486 |
| NP_001034239 NP_001034240 NP_001171256 NP_001171257 NP_001171258
| NP_033981 |
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Локус (UCSC) | Хр. 11: 35.14 – 35.23 Mb | Хр. 2: 102.64 – 102.73 Mb |
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PubMed search | [1] | [2] |
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Вікідані |
Див./Ред. для людей | Див./Ред. для мишей |
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