LHX2 |
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識別號 |
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别名 | LHX2;, LH2, hLhx2, LIM homeobox 2 |
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外部ID | OMIM:603759 MGI:96785 HomoloGene:55848 GeneCards:LHX2 |
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基因位置(人类) |
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| 染色体 | 9號染色體[1] |
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| 基因座 | 9q33.3 | 起始 | 124,001,670 bp[1] |
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终止 | 124,033,301 bp[1] |
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基因位置(小鼠) |
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| 染色体 | 小鼠2号染色体[2] |
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| 基因座 | 2|2 B | 起始 | 38,229,293 bp[2] |
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终止 | 38,259,745 bp[2] |
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RNA表达模式 |
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查阅更多表达数据 |
基因本體 |
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分子功能 | • 金屬離子結合 • sequence-specific DNA binding • chromatin binding • DNA结合 • RNA polymerase II cis-regulatory region sequence-specific DNA binding • DNA-binding transcription activator activity, RNA polymerase II-specific • DNA-binding transcription factor activity, RNA polymerase II-specific • 转录因子结合 • RNA polymerase II transcription regulatory region sequence-specific DNA binding
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細胞組分 | • 细胞核 • 胞內
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生物學過程 | • negative regulation of transcription regulatory region DNA binding • mesoderm development • telencephalon development • neural tube closure • retina development in camera-type eye • 大脑皮质的组织发生 • transcription, DNA-templated • 轴突导向 • axon extension • hair follicle development • maintenance of epithelial cell apical/basal polarity • 神经发生 • brain development • olfactory bulb development • 神經系統的發育 • dorsal/ventral pattern formation • positive regulation of transcription, DNA-templated • regulation of transcription, DNA-templated • positive regulation of transcription by RNA polymerase II • neuron differentiation • anatomical structure formation involved in morphogenesis • telencephalon regionalization • transcription by RNA polymerase II • negative regulation of gene expression, epigenetic • negative regulation of neurogenesis • positive regulation of neural precursor cell proliferation
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Sources:Amigo / QuickGO |
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直系同源 |
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物種 | 人類 | 小鼠 |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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mRNA序列 | | |
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蛋白序列 | | |
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基因位置(UCSC) | Chr 9: 124 – 124.03 Mb | Chr 2: 38.23 – 38.26 Mb |
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PubMed查找 | [3] | [4] |
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維基數據 |
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