ATC代码 |
L 抗肿瘤药及免疫制剂(Antineoplastic and immunomodulating agents) |
L01 抗肿瘤药(Antineoplastic agents) |
L02 内分泌治疗(Endocrine therapy) |
L03 免疫增强剂(Immunostimulants) |
L04 免疫抑制剂(Immunosuppressants) |
A·B·C·D·G·H·QI·J·L·M·N·P·R·S·V |
ATC代码L02(内分泌疗法)是解剖学治疗学及化学分类系统的一个药物分组,这是由世界卫生组织药物统计方法整合中心(The WHO Collaborating Centre for Drug Statistics Methodology)所制定的药品及其它医用产品的官方分类系统。分组L02是L抗肿瘤药及免疫用药的一部分。[1]
兽用代码(ATCvet码)可以在人用ATC代码前加Q字母:QL02等[2]。
国家ATC分类可能包括列表中没有的其它分类,列表为世界卫生组织(WHO)版本。
- L02AA01 己烯雌酚(Diethylstilbestrol)
- L02AA02 聚雌二醇磷酸酯(Polyestradiol phosphate)
- L02AA03 炔雌醇(Ethinylestradiol)
- L02AA04 磷雌酚(Fosfestrol)
- L02AB01 甲地孕酮(Megestrol)
- L02AB02 甲羟孕酮(Medroxyprogesterone)
- L02AB03 孕诺酮(Gestonorone)
L02AE 促性腺素释放激素同系物(Gonadotropin-releasing hormone analogues)
- L02AE01 布舍瑞林(Buserelin)
- L02AE02 亮丙瑞林(Leuprorelin)
- L02AE03 戈舍瑞林(Goserelin)
- L02AE04 曲普瑞林(Triptorelin)
L02AX 其它激素(Other hormones)
L02BA 抗雌激素类(Anti-estrogens)
- L02BA01 他莫昔芬(Tamoxifen)
- L02BA02 托瑞米芬(Toremifene)
- L02BA03 氟维司群(Fulvestrant)
L02BB 抗雄激素类(Anti-androgens)
- L02BB01 氟他胺(Flutamide)
- L02BB02 尼鲁米特(Nilutamide)
- L02BB03 比卡鲁胺(Bicalutamide)
L02BG 酶抑制药类(Aromatase inhibitors)
- L02BG01 氨鲁米特(Aminogluthetimide)
- L02BG02 福美坦(Formestane)
- L02BG03 阿那曲唑(Anastrozole)
- L02BG04 来曲唑(Letrozole)
- L02BG05 伏氯唑(Vorozole)
- L02BG06 依西美坦(Exemestane)
- L02BX01 阿巴瑞克(Abarelix)
- L02BX02 地格瑞克(Degarelix)
- L02BX03 阿比特龙(Abiraterone)
参考文献
- ^ ATC Index. WHO Collaborating Centre for Drug Statistics Methodology.
- ^ ATCvet Index. WHO Collaborating Centre for Drug Statistics Methodology.
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| 受体 | |
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| 酶 (抑制剂) | | - 22-ABC
- 3,3′-Dimethoxybenzidine
- 3-Methoxybenzidine
- Aminoglutethimide
- Cyanoketone
- Danazol
- Etomidate
- Mitotane
- Trilostane
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| 17α-羟化酶, 17,20-裂合酶 | |
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| 3β-HSD (I, II) | |
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| 17β-HSD (I-XIV) | |
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| | - 22-Oxime
- Alfatradiol
- Azelaic acid
- β-Sitosterol
- Bexlosteride
- Dutasteride
- 表睾酮
- Epristeride
- Finasteride
- Izonsteride
- L-39
- Lapisteride
- Polyunsaturated fatty acids (α-linolenic acid, linoleic acid, γ-linolenic acid, oleic acid)
- Turosteride
- Vitamin B6
- 锌
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| | - 1,4,6-Androstatriene-3,17-dione
- 4-Androstene-3,6,17-trione
- 4-Cyclohexylaniline
- 4-Hydroxytestosterone
- 5α-DHNET
- Abyssinone II
- Aminoglutethimide
- Anastrozole
- 抗坏血酸(维生素C)
- Atamestane
- Bifonazole
- CGP-45,688
- CGS-47,645
- Clotrimazole
- 双氢睾酮
- Difeconazole
- Econazole
- Exemestane
- Fadrozole
- Fenarimol
- Finrozole
- Formestane
- Imazalil
- Isoconazole
- Ketoconazole
- Letrozole
- Liarozole
- MEN-11066
- Miconazole
- Minamestane
- Nimorazole
- NKS01
- ORG-33,201
- Penconazole
- Plomestane
- Prochloraz
- Propioconazole
- Pyridoglutethimide
- Rogletimide
- Rotenone
- Talarozole
- Testolactone
- Tioconazole
- Triadimefon
- Triadimenol
- Troglitazone
- Vorozole
- YM511
- 锌
Note: 21-Hydroxylase inhibitors may also affect androgen levels as they prevent metabolism of androgen steroid precursors. |
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| 其他 | | |
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| 间接 | - Estrogens/Antiestrogens (see here)
- GnRH agonists/antagonists (see here)
- Gonadotropins/Antigonadotropins (see here)
- Plasma proteins (SHBG, ABP, Albumin)
- Progestogens/Antiprogestins (see here)
- Prolactin
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雌激素受体(英语:Estrogen receptor)调节剂 |
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| 受体 | 雌激素受体 (雌激素受体α, 雌激素受体β) | |
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| G蛋白偶联雌激素受体 | |
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| 酶 (抑制剂) | | - 22-ABC
- 3,3′-Dimethoxybenzidine
- 3-Methoxybenzidine
- Aminoglutethimide(英语:Aminoglutethimide)
- Cyanoketone(英语:Cyanoketone)
- 達那唑
- Etomidate(英语:Etomidate)
- Mitotane(英语:Mitotane)
- Trilostane(英语:Trilostane)
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| 17α-羟基化酶 17,20-碳链裂解酶 | - 22-ABC
- 22-Oxime
- Abiraterone(英语:Abiraterone)
- 聯苯芐唑
- 克催瑪汝
- Cyanoketone(英语:Cyanoketone)
- 環丙孕酮
- 達那唑
- 益康唑
- Galeterone(英语:Galeterone)
- 孕三烯酮
- Isoconazole(英语:Isoconazole)
- 酮康唑
- L-39
- Liarozole(英语:Liarozole)
- LY-207,320
- MDL-27,302
- 咪康唑
- 美服培酮
- Orteronel(英语:Orteronel)
- 吡格列酮
- 羅格列酮
- 螺内酯
- 司坦唑醇
- SU-10,603
- TGF-β
- 噻康唑
- Troglitazone(英语:Troglitazone)
- VN/87-1
- YM116
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| 3β-HSD(英语:3β-Hydroxysteroid dehydrogenase) | - 4-MA
- Azastene(英语:Azastene)
- Cyanoketone(英语:Cyanoketone)
- 達那唑
- Epostane(英语:Epostane)
- 染料木素
- 孕三烯酮
- 美替拉酮
- Oxymetholone(英语:Oxymetholone)
- 吡格列酮
- 羅格列酮
- Trilostane(英语:Trilostane)
- Troglitazone(英语:Troglitazone)
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| | - 1,4,6-Androstatriene-3,17-dione(英语:1,4,6-Androstatriene-3,17-dione)
- 4-雄烯-3,6,17-三酮
- 4-Cyclohexylaniline
- 4-Hydroxytestosterone(英语:4-Hydroxytestosterone)
- 5α-DHNET(英语:5α-Dihydro-19-norethisterone)
- Abyssinone II
- Aminoglutethimide(英语:Aminoglutethimide)
- Anastrozole(英语:Anastrozole)
- 抗壞血酸 (維生素C)
- Atamestane(英语:Atamestane)
- 聯苯芐唑
- CGP-45,688
- CGS-47,645
- 克催瑪汝
- DHT
- Difeconazole
- 益康唑
- 依西美坦
- Fadrozole(英语:Fadrozole)
- Fenarimol(英语:Fenarimol)
- Finrozole(英语:Finrozole)
- Formestane(英语:Formestane)
- 抑霉唑
- Isoconazole(英语:Isoconazole)
- 酮康唑
- 來曲唑
- Liarozole(英语:Liarozole)
- MEN-11066
- 咪康唑
- Minamestane(英语:Minamestane)
- Nimorazole(英语:Nimorazole)
- NKS01
- ORG-33,201
- 戊菌唑
- 普洛美坦
- 咪鲜胺
- 丙环唑
- Pyridoglutethimide(英语:Pyridoglutethimide)
- Rogletimide
- 魚藤酮
- Talarozole(英语:Talarozole)
- Testolactone(英语:Testolactone)
- 噻康唑
- Triadimefon(英语:Triadimefon)
- 三唑醇
- Troglitazone(英语:Troglitazone)
- Vorozole(英语:Vorozole)
- YM511
- 鋅
Note: 5α-reductase and 21-hydroxylase(英语:21-hydroxylase) inhibitors may also affect estrogen levels as they prevent metabolism of estrogen steroid precursors. |
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| Other | | |
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| Indirect | - 雄激素/抗雄激素 (更多)
- 骨化三醇 (维生素D的一種)
- GnRH agonist(英语:Gonadotropin-releasing hormone agonist)s/antagonist(英语:Gonadotropin-releasing hormone antagonist)s (see here)
- 促性腺激素//Antigonadotropin(英语:Antigonadotropin)s (更多)
- 血浆蛋白 (SHBG, ABP, Albumin)
- 孕激素/Antiprogestin(英语:Antiprogestin)s (更多)
- 催乳素
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孕酮受体調控劑(英语:receptor modulator) |
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| PR | 受體致活劑 | |
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| Mixed (SPRMs(英语:Selective progesterone receptor modulator)) | - Apigenin(英语:Apigenin)
- Asoprisnil(英语:Asoprisnil)
- Asoprisnil ecamate
- Guggulsterone(英语:Guggulsterone)
- 山柰酚
- J1042
- LG-120838
- Naringenin(英语:Naringenin)
- PRA-910
- 丁香酸
- Telapristone(英语:Telapristone)
- 受體拮抗劑: 美服培酮
- Org-31710
- Org-33628
- Ulipristal acetate(英语:Ulipristal acetate)
- ZK-137316
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| Antagonists | - 3α-Hydroxytibolone
- 3β-Hydroxytibolone
- 阿来司酮
- 利洛司酮
- 洛那立生
- 奥那司酮
- 托立司酮
- 丙戊酸
- 维拉立生
- 扎诺特隆(英语:Zanoterone)
- ZM-150271
- ZM-172406
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| mPRs(英语:Membrane progesterone receptor) (PAQRs(英语:Progestin and adipoQ receptor)) | 受體致活劑 | - 5α-Dihydroprogesterone(英语:5α-Dihydroprogesterone)
- 5β-Dihydroprogesterone(英语:5β-Dihydroprogesterone)
- 11-脱氧皮质酮
- 17α-Hydroxyprogesterone(英语:17α-Hydroxyprogesterone)
- 17α,21-Dihydroxyprogesterone
- Allopregnanolone(英语:Allopregnanolone)
- 美服培酮
- 孕烯醇酮
- 孕酮
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| Antagonists | |
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| 參見: 雄激素 • 雌激素 • Glucocorticoidics • Mineralocorticoidics |
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