Sukcinilsulfatiazol : Osobine, Reference, Literatura, Spoljašnje veze Википедија

Sukcinilsulfatiazol

Sukcinilsulfatiazol
Klinički podaci

Drugs.com	Monografija
Identifikatori
ATC kod	A07AB04 (WHO)
PubChem	CID 5315
UNII	RSS8647O4S^Y
KEGG	D07060^Y
Hemijski podaci
Formula	C₁₃H₁₃N₃O₅S₂
Molarna masa	355,389
SMILES OC(=O)CCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nccs2
InChI InChI=1S/C13H13N3O5S2/c17-11(5-6-12(18)19)15-9-1-3-10(4-2-9)23(20,21)16-13-14-7-8-22-13/h1-4,7-8H,5-6H2,(H,14,16)(H,15,17)(H,18,19)^Y Key:SKVLYVHULOWXTD-UHFFFAOYSA-N^Y

Sukcinilsulfatiazol je organsko jedinjenje, koje sadrži 13 atoma ugljenika i ima molekulsku masu od 355,389 Da.

Osobine

Osobina	Vrednost
Broj akceptora vodonika	6
Broj donora vodonika	3
Broj rotacionih veza	7
Particioni koeficijent^[1] (ALogP)	0,3
Rastvorljivost^[2] (logS, log(mol/L))	-3,4
Polarna površina^[3] (PSA, Å²)	162,1

^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o.
^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t.
^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e.

Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803.
Thomas L. Lemke; David A. Williams, ур. (2007). Foye's Principles of Medicinal Chemistry (6. изд.). Baltimore: Lippincott Willams & Wilkins. ISBN 0781768799.