Transaminaza aminokiselina razgranatog lanca
| Transaminaza aminokiselina razgranatog lanca | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Transaminaza aminokiselina razgranatog lanca hexamer, Burkholderia pseudomallei | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.6.1.42 | ||||||||
| CAS broj | 9054-65-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Transaminaza aminokiselina razgranatog lanca (EC 2.6.1.42, transaminaza B, aminotransferaza aminokiselina razgranatog lanca, transferaza aminokiselina razgranatog lanca, aminotransferaza razgranatih lanaca, aminotransferaza L-aminokiselina razgranatog lanca) je enzim sa sistematskim imenom aminokiselina razgranatog lanca:2-oksoglutarat aminotransferaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-leucin + 2-oksoglutarat 4-metil-2-oksopentanoat + L-glutamat
Ovaj enzim takođe deluje na L-izoleucin i L-valin.
Reference
- ↑ Aki, K., Ogawa, K. and Ichihara, A. (1968). „Transaminases of branched chain amino acids. IV. Purification and properties of two enzymes from rat liver”. Biochim. Biophys. Acta 159: 276-284. PMID 4968655.
- ↑ Aki, K., Yokojima, A. and Ichihara, A. (1969). „Transaminase of branched chain amino acids. VI. Purification and properties of the hog brain enzyme”. J. Biochem. (Tokyo) 65: 539-544. PMID 4979711.
- ↑ Ichihara, A. and Koyama, E. (1966). „Transaminase of branched chain amino acids. I. Branched chain amino acids-α-ketoglutarate transaminase”. J. Biochem. (Tokyo) 59: 160-169. PMID 5943594.
- ↑ Taylor, R.T. and Jenkins, W.T. (1966). „Leucine aminotransferase. II. Purification and characterization”. J. Biol. Chem. 241: 4396-4405. PMID 5922965.
- ↑ Rudman, D. and Meister, A. (1953). „Transamination in Escherichia coli”. J. Biol. Chem. 200: 591-604. PMID 13034817.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH Branched-chain-amino-acid+transaminase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
