GOPC
GOPC | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identificadores | |||||||||||||||||||||||||||||||||||||||||||||||||||
Nomes alternativos | GOPC | ||||||||||||||||||||||||||||||||||||||||||||||||||
IDs externos | OMIM: 606845 HomoloGene: 10695 GeneCards: GOPC | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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A PDZ associada ao Golgi e proteína contendo motivo espiralado é uma proteína que em humanos é codificada pelo gene GOPC.[2][3][4]
PIST é uma proteína de Golgi contendo o domínio PDZ. Os domínios PDZ contêm aproximadamente 90 aminoácidos e ligam o terminal C extremo de proteínas de uma maneira específica da seqüência.[4]
Interações
O GOPC demonstrou interagir com GRID2,[5] BECN1,[5] RHOQ,[2]ACCN3,[6] CFTR[7][8] e CSPG5.[9]
Referências
- ↑ «Human PubMed Reference:»
- ↑ a b Neudauer CL, Joberty G, Macara IG (fevereiro de 2001). «PIST: a novel PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10». Biochem Biophys Res Commun. 280 (2): 541–7. PMID 11162552. doi:10.1006/bbrc.2000.4160
- ↑ Yao R, Maeda T, Takada S, Noda T (agosto de 2001). «Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled». Biochem Biophys Res Commun. 286 (4): 771–8. PMID 11520064. doi:10.1006/bbrc.2001.5430
- ↑ a b «Entrez Gene: GOPC golgi associated PDZ and coiled-coil motif containing»
- ↑ a b Yue, Zhenyu; Horton Antony; Bravin Monica; DeJager Philip L; Selimi Fekrije; Heintz Nathaniel (agosto de 2002). «A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice». United States. Neuron. 35 (5): 921–33. ISSN 0896-6273. PMID 12372286. doi:10.1016/S0896-6273(02)00861-9
- ↑ Hruska-Hageman, Alesia M; Benson Christopher J; Leonard A Soren; Price Margaret P; Welsh Michael J (novembro de 2004). «PSD-95 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+- gated current». United States. J. Biol. Chem. 279 (45): 46962–8. ISSN 0021-9258. PMID 15317815. doi:10.1074/jbc.M405874200
- ↑ Cheng, Jie; Moyer Bryan D; Milewski Michal; Loffing Johannes; Ikeda Masahiro; Mickle John E; Cutting Garry R; Li Min; Stanton Bruce A; Guggino William B (fevereiro de 2002). «A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression». United States. J. Biol. Chem. 277 (5): 3520–9. ISSN 0021-9258. PMID 11707463. doi:10.1074/jbc.M110177200
- ↑ Gentzsch, Martina; Cui Liying; Mengos April; Chang Xiu-Bao; Chen Jey-Hsin; Riordan John R (fevereiro de 2003). «The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins». United States. J. Biol. Chem. 278 (8): 6440–9. ISSN 0021-9258. PMID 12471024. doi:10.1074/jbc.M211050200
- ↑ Hassel, Burkhard; Schreff Matthias; Stube Eva-Maria; Blaich Uta; Schumacher Stefan (outubro de 2003). «CALEB/NGC interacts with the Golgi-associated protein PIST». United States. J. Biol. Chem. 278 (41): 40136–43. ISSN 0021-9258. PMID 12885772. doi:10.1074/jbc.M305577200
Leitura adicional
- Loo MA, Jensen TJ, Cui L, et al. (1999). «Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome». EMBO J. 17 (23): 6879–87. PMC 1171036
. PMID 9843494. doi:10.1093/emboj/17.23.6879
- Charest A, Lane K, McMahon K, Housman DE (2001). «Association of a novel PDZ domain-containing peripheral Golgi protein with the Q-SNARE (Q-soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor) protein syntaxin 6». J. Biol. Chem. 276 (31): 29456–65. PMID 11384996. doi:10.1074/jbc.M104137200
- Cheng J, Moyer BD, Milewski M, et al. (2002). «A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression». J. Biol. Chem. 277 (5): 3520–9. PMID 11707463. doi:10.1074/jbc.M110177200
- Yao R, Ito C, Natsume Y, et al. (2002). «Lack of acrosome formation in mice lacking a Golgi protein, GOPC». Proc. Natl. Acad. Sci. U.S.A. 99 (17): 11211–6. PMC 123235
. PMID 12149515. doi:10.1073/pnas.162027899
- Yue Z, Horton A, Bravin M, et al. (2002). «A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice». Neuron. 35 (5): 921–33. PMID 12372286. doi:10.1016/S0896-6273(02)00861-9
- Gentzsch M, Cui L, Mengos A, et al. (2003). «The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins». J. Biol. Chem. 278 (8): 6440–9. PMID 12471024. doi:10.1074/jbc.M211050200
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). «Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences». Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899
- Charest A, Kheifets V, Park J, et al. (2003). «Oncogenic targeting of an activated tyrosine kinase to the Golgi apparatus in a glioblastoma». Proc. Natl. Acad. Sci. U.S.A. 100 (3): 916–21. PMC 298701
. PMID 12538861. doi:10.1073/pnas.242741799
- Charest A, Lane K, McMahon K, et al. (2003). «Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del(6)(q21q21)». Genes Chromosomes Cancer. 37 (1): 58–71. PMID 12661006. doi:10.1002/gcc.10207
- Hassel B, Schreff M, Stube EM, et al. (2003). «CALEB/NGC interacts with the Golgi-associated protein PIST». J. Biol. Chem. 278 (41): 40136–43. PMID 12885772. doi:10.1074/jbc.M305577200
- Cheng J, Wang H, Guggino WB (2004). «Modulation of mature cystic fibrosis transmembrane regulator protein by the PDZ domain protein CAL». J. Biol. Chem. 279 (3): 1892–8. PMID 14570915. doi:10.1074/jbc.M308640200
- Mungall AJ, Palmer SA, Sims SK, et al. (2003). «The DNA sequence and analysis of human chromosome 6». Nature. 425 (6960): 805–11. PMID 14574404. doi:10.1038/nature02055
- Brill LM, Salomon AR, Ficarro SB, et al. (2004). «Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry». Anal. Chem. 76 (10): 2763–72. PMID 15144186. doi:10.1021/ac035352d
- Hruska-Hageman AM, Benson CJ, Leonard AS, et al. (2004). «PSD-95 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+- gated current». J. Biol. Chem. 279 (45): 46962–8. PMID 15317815. doi:10.1074/jbc.M405874200
- He J, Bellini M, Xu J, et al. (2005). «Interaction with cystic fibrosis transmembrane conductance regulator-associated ligand (CAL) inhibits beta1-adrenergic receptor surface expression». J. Biol. Chem. 279 (48): 50190–6. PMID 15358775. doi:10.1074/jbc.M404876200
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). «The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)». Genome Res. 14 (10B): 2121–7. PMC 528928
. PMID 15489334. doi:10.1101/gr.2596504
- Cheng J, Wang H, Guggino WB (2005). «Regulation of cystic fibrosis transmembrane regulator trafficking and protein expression by a Rho family small GTPase TC10». J. Biol. Chem. 280 (5): 3731–9. PMID 15546864. doi:10.1074/jbc.M410026200
- Hicks SW, Machamer CE (2005). «Isoform-specific interaction of golgin-160 with the Golgi-associated protein PIST». J. Biol. Chem. 280 (32): 28944–51. PMID 15951434. doi:10.1074/jbc.M504937200
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