GPR123
ADGRA1 | |||||||||||||||||||||||||
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Pengidentifikasi | |||||||||||||||||||||||||
Alias | ADGRA1, GPR123, adhesion G protein-coupled receptor A1 | ||||||||||||||||||||||||
ID eksternal | OMIM: 612302 MGI: 1277167 HomoloGene: 18582 GeneCards: ADGRA1 | ||||||||||||||||||||||||
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Ortolog | |||||||||||||||||||||||||
Spesies | Manusia | Tikus | |||||||||||||||||||||||
Entrez |
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Ensembl |
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UniProt |
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RefSeq (mRNA) |
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RefSeq (protein) |
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Lokasi (UCSC) | Chr 10: 133.09 – 133.13 Mb | Chr 7: 139.41 – 139.46 Mb | |||||||||||||||||||||||
Pencarian PubMed | [3] | [4] | |||||||||||||||||||||||
Wikidata | |||||||||||||||||||||||||
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GPR123 (nama resmi: ADGRA1) adalah protein pada manusia disandi oleh gen GPR123.[5][6] GPR123 adalah anggota dari keluarga reseptor GPCR adhesi. Anggota keluarga biasanya ditandai dengan daerah ekstraseluler diperpanjang dengan sejumlah variabel domain protein digabungkan ke domain TM7 melalui domain dikenal sebagai domain GAIN (GPCR-Autoproteolysis INducing).[7][8][9]
Referensi
- ^ a b c GRCh38: Ensembl release 89: ENSG00000197177 - Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025475 - Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Fredriksson R, Gloriam DE, Hoglund PJ, Lagerstrom MC, Schioth HB (Feb 2003). "There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini". Biochem Biophys Res Commun. 301 (3): 725–34. doi:10.1016/S0006-291X(03)00026-3. PMID 12565841.
- ^ "Entrez Gene: GPR123 G protein-coupled receptor 123". Diarsipkan dari versi asli tanggal 2023-07-26.
- ^ Stacey M, Yona S (2011). AdhesionGPCRs: Structure to Function (Advances in Experimental Medicine and Biology). Berlin: Springer. ISBN 1-4419-7912-3.
- ^ Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002). "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions". FEBS Lett. 531 (3): 407–14. doi:10.1016/S0014-5793(02)03574-3. PMID 12435584.
- ^ Araç D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Südhof TC, Brunger AT (March 2012). "A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis". EMBO J. 31 (6): 1364–78. doi:10.1038/emboj.2012.26. PMC 3321182
. PMID 22333914.