SATB1 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/2/28/Protein_SATB1_PDB_1yse.png/250px-Protein_SATB1_PDB_1yse.png) |
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Structures disponibles |
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PDB | Recherche d'orthologue: PDBe RCSB |
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Identifiants PDB |
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1YSE, 2L1P, 2O49, 2O4A, 3NZL, 3TUO, 2MW8 |
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Identifiants |
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Aliases | SATB1 |
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IDs externes | OMIM: 602075 MGI: 105084 HomoloGene: 2232 GeneCards: SATB1 |
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Position du gène (Homme) |
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![Chromosome 3 humain](//upload.wikimedia.org/wikipedia/commons/thumb/3/39/Ideogram_human_chromosome_3.svg/300px-Ideogram_human_chromosome_3.svg.png) | Chr. | Chromosome 3 humain[1] |
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| Locus | 3p24.3 | Début | 18,345,377 bp[1] |
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Fin | 18,445,588 bp[1] |
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Position du gène (Souris) |
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![Chromosome 17 (souris)](//upload.wikimedia.org/wikipedia/commons/thumb/1/13/Ideogram_house_mouse_chromosome_17.svg/260px-Ideogram_house_mouse_chromosome_17.svg.png) | Chr. | Chromosome 17 (souris)[2] |
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| Locus | 17|17 C | Début | 52,043,215 bp[2] |
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Fin | 52,140,318 bp[2] |
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Expression génétique |
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Bgee | Humain | Souris (orthologue) |
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Fortement exprimé dans | - cortex orbitofrontal
- frontal pole
- thymus
- Brodmann area 46
- lobe pariétal
- gyrus postcentral
- parotide
- Brodmann area 10
- Cortex entorhinal
- Brodmann area 23
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| Fortement exprimé dans | - thymus
- molaire
- barrel cortex
- zygote
- secondary oocyte
- Rostral migratory stream
- substantia nigra
- glande lacrymale
- muscle vaste latéral
- sang
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| Plus de données d'expression de référence |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/f/f5/PBB_GE_SATB1_203408_s_at_fs.png/250px-PBB_GE_SATB1_203408_s_at_fs.png) | Plus de données d'expression de référence |
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Gene Ontology |
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Fonction moléculaire | - liaison ADN
- RNA polymerase II transcription regulatory region sequence-specific DNA binding
- DNA-binding transcription factor activity
- liaison de chromatine
- liaison protéique
- DNA-binding transcription repressor activity, RNA polymerase II-specific
- double-stranded DNA binding
- DNA-binding transcription factor activity, RNA polymerase II-specific
- sequence-specific DNA binding
| Composant cellulaire | - PML body
- matrice nucléaire
- nucléoplasme
- chromatine
- noyau
- corps nucléaire
| Processus biologique | - réflexe
- CD4-positive, alpha-beta T cell differentiation
- CD8-positive, alpha-beta T cell differentiation
- Remodelage de la chromatine
- activated T cell proliferation
- regulation of transcription, DNA-templated
- negative regulation of transcription by RNA polymerase II
- organisation de la chromatine
- transcription, DNA-templated
- epidermis development
- histone methylation
- viral process
- T cell activation
| Sources:Amigo / QuickGO |
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Orthologues |
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Espèces | Homme | Souris |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001131010 NM_001195470 NM_002971 NM_001322871 NM_001322872
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NM_001322873 NM_001322874 NM_001322875 NM_001322876 |
| NM_001163630 NM_001163631 NM_001163632 NM_009122 NM_001357636
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NM_001357637 NM_001357638 NM_001357640 |
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RefSeq (protéine) | NP_001124482 NP_001182399 NP_001309800 NP_001309801 NP_001309802
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NP_001309803 NP_001309804 NP_001309805 NP_002962 |
| NP_001157102 NP_001157103 NP_001157104 NP_033148 NP_001344565
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NP_001344566 NP_001344567 NP_001344569 |
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Localisation (UCSC) | Chr 3: 18.35 – 18.45 Mb | Chr 17: 52.04 – 52.14 Mb |
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Publication PubMed | [3] | [4] |
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Wikidata |
Voir/Editer Humain | Voir/Editer Souris |
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