Protein found in humans
ZNF157 |
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Identifiers |
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Aliases | ZNF157, HZF22, zinc finger protein 157 |
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External IDs | OMIM: 300024; HomoloGene: 130519; GeneCards: ZNF157; OMA:ZNF157 - orthologs |
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Gene location (Human) |
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| Chr. | X chromosome (human)[1] |
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| Band | Xp11.3 | Start | 47,370,578 bp[1] |
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End | 47,414,498 bp[1] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - ventricular zone
- ganglionic eminence
- right uterine tube
- gonad
- olfactory zone of nasal mucosa
- islet of Langerhans
- cerebellar cortex
- cerebellar hemisphere
- right hemisphere of cerebellum
- anterior pituitary
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| | More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - DNA-binding transcription factor activity
- DNA binding
- metal ion binding
- nucleic acid binding
- DNA-binding transcription factor activity, RNA polymerase II-specific
| Cellular component | - intracellular anatomical structure
- nucleus
| Biological process | - regulation of transcription, DNA-templated
- negative regulation of transcription by RNA polymerase II
- transcription, DNA-templated
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr X: 47.37 – 47.41 Mb | n/a |
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PubMed search | [2] | n/a |
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Wikidata |
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Zinc finger protein 157 is a protein that in humans is encoded by the ZNF157 gene. [3]
Function
This gene product is a likely zinc finger family transcription factor. It contains KRAB-A and KRAB-B domains that act as transcriptional repressors in related proteins, and multiple zinc finger DNA binding motifs and finger linking regions characteristic of the Kruppel family. This gene is part of a gene cluster on chromosome Xp11.23.
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000147117 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Zinc finger protein 157". Retrieved 2016-03-17.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.