UBXD2

Protein-coding gene in the species Homo sapiens

UBXN4

Available structures

PDB

Ortholog search: PDBe RCSB

List of PDB id codes
2KXJ

Identifiers

Aliases

UBXN4, UBXD2, UBXDC1, erasin, UBX domain protein 4

External IDs

OMIM: 611216; MGI: 1915062; HomoloGene: 40962; GeneCards: UBXN4; OMA:UBXN4 - orthologs

Gene location (Human)

Chr.	Chromosome 2 (human)^[1]

Band	2q21.3	Start	135,741,734 bp^[1]
Band	2q21.3	End	135,785,056 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 1 (mouse)^[2]

Band	1\|1 E3	Start	128,171,701 bp^[2]
Band	1\|1 E3	End	128,207,115 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

sperm

pylorus

cardia

secondary oocyte

optic nerve

seminal vesicula

body of pancreas

nipple

endometrium

corpus epididymis

Top expressed in

lacrimal gland

Rostral migratory stream

left lobe of liver

tail of embryo

supraoptic nucleus

prostate

salivary gland

lobe of prostate

seminal vesicula

retinal pigment epithelium

More reference expression data

BioGPS


More reference expression data

Gene ontology
Molecular function	protein binding
Cellular component	nuclear envelope endoplasmic reticulum endoplasmic reticulum membrane nucleus membrane cytosol
Biological process	response to unfolded protein ubiquitin-dependent ERAD pathway
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


23190


67812

Ensembl


ENSG00000144224


ENSMUSG00000026353

UniProt


Q92575


Q8VCH8

RefSeq (mRNA)


NM_014607


NM_026390 NM_001356529

RefSeq (protein)


NP_055422


NP_080666 NP_001343458

Location (UCSC)

Chr 2: 135.74 – 135.79 Mb

Chr 1: 128.17 – 128.21 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

UBX domain-containing protein 4 is a protein that in humans is encoded by the UBXN4 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000144224 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026353 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Liang J, Yin C, Doong H, Fang S, Peterhoff C, Nixon RA, Monteiro MJ (Sep 2006). "Characterization of erasin (UBXD2): a new ER protein that promotes ER-associated protein degradation". J Cell Sci. 119 (Pt 19): 4011–24. doi:10.1242/jcs.03163. PMID 16968747. S2CID 1194226.
^ "Entrez Gene: UBXD2 UBX domain containing 2".

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