Tetrahydrodipicolinate N-acetyltransferase
tetrahydrodipicolinate N-acetyltransferase | |||||||||
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Identifiers | |||||||||
EC no. | 2.3.1.89 | ||||||||
CAS no. | 83588-91-4 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a tetrahydrodipicolinate N-acetyltransferase (EC 2.3.1.89) is an enzyme that catalyzes the chemical reaction
- acetyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O CoA + L-2-acetamido-6-oxoheptanedioate
The 3 substrates of this enzyme are acetyl-CoA, (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate, and H2O, whereas its two products are CoA and L-2-acetamido-6-oxoheptanedioate.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N2-acetyltransferase. Other names in common use include tetrahydrodipicolinate acetylase, tetrahydrodipicolinate:acetyl-CoA acetyltransferase, acetyl-CoA:L-2,3,4,5-tetrahydrodipicolinate N2-acetyltransferase, acetyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate, and 2-N-acetyltransferase. This enzyme participates in lysine biosynthesis.
References
- Chatterjee SP, White PJ (1982). "Activities and regulation of the enzymes of lysine biosynthesis in a lysine-excreting strain of Bacillus megaterium". J. Gen. Microbiol. 128: 1073–1081. doi:10.1099/00221287-128-5-1073.
- v
- t
- e
- acetyltransferases: Acetyl-Coenzyme A acetyltransferase
- N-Acetylglutamate synthase
- Choline acetyltransferase
- Dihydrolipoyl transacetylase
- Acetyl-CoA C-acyltransferase
- Beta-galactoside transacetylase
- Chloramphenicol acetyltransferase
- N-acetyltransferase
- Histone acetyltransferase
- Citrate synthase
- Decylcitrate synthase
- Citrate (Re)-synthase
- Decylhomocitrate synthase
- 2-methylcitrate synthase
- 2-ethylmalate synthase
- 3-ethylmalate synthase
- ATP citrate lyase
- Malate synthase
- HMG-CoA synthase
- 2-hydroxyglutarate synthase
- 3-propylmalate synthase
- 2-isopropylmalate synthase
- Homocitrate synthase
- Sulfoacetaldehyde acetyltransferase