TSPYL1

Protein-coding gene in humans
TSPYL1
Identifiers
AliasesTSPYL1, TSPYL, TSPY-like 1, TSPY like 1
External IDsOMIM: 604714; MGI: 1298395; HomoloGene: 22522; GeneCards: TSPYL1; OMA:TSPYL1 - orthologs
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for TSPYL1
Genomic location for TSPYL1
Band6q22.1Start116,267,760 bp[1]
End116,279,930 bp[1]
Gene location (Mouse)
Chromosome 10 (mouse)
Chr.Chromosome 10 (mouse)[2]
Chromosome 10 (mouse)
Genomic location for TSPYL1
Genomic location for TSPYL1
Band10|10 B1Start34,158,186 bp[2]
End34,161,271 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • germinal epithelium

  • lateral nuclear group of thalamus

  • pons

  • Brodmann area 23

  • Pars compacta

  • seminal vesicula

  • external globus pallidus

  • superior vestibular nucleus

  • parietal lobe

  • Skeletal muscle tissue of rectus abdominis
Top expressed in
  • ventral tegmental area

  • habenula

  • dorsomedial hypothalamic nucleus

  • pontine nuclei

  • lateral hypothalamus

  • globus pallidus

  • Gonadal ridge

  • paraventricular nucleus of hypothalamus

  • median eminence

  • arcuate nucleus
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • enzyme binding
Cellular component
  • nucleus
  • nucleolus
Biological process
  • nucleosome assembly
  • biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

7259

22110

Ensembl

ENSG00000189241

ENSMUSG00000047514

UniProt

Q9H0U9

O88852

RefSeq (mRNA)

NM_003309

NM_009433

RefSeq (protein)

NP_003300

NP_033459

Location (UCSC)Chr 6: 116.27 – 116.28 MbChr 10: 34.16 – 34.16 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Testis-specific Y-encoded-like protein 1 is a protein that in humans is encoded by the TSPYL1 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000189241 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000047514 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Vogel T, Dittrich O, Mehraein Y, Dechend F, Schnieders F, Schmidtke J (Oct 1998). "Murine and human TSPYL genes: novel members of the TSPY-SET-NAP1L1 family". Cytogenet Cell Genet. 81 (3–4): 265–70. doi:10.1159/000015042. PMID 9730615. S2CID 46829106.
  6. ^ "Entrez Gene: TSPYL1 TSPY-like 1".

Further reading

  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Puffenberger EG, Hu-Lince D, Parod JM, et al. (2004). "Mapping of sudden infant death with dysgenesis of the testes syndrome (SIDDT) by a SNP genome scan and identification of TSPYL loss of function". Proc. Natl. Acad. Sci. U.S.A. 101 (32): 11689–94. Bibcode:2004PNAS..10111689P. doi:10.1073/pnas.0401194101. PMC 511011. PMID 15273283.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • de Andrade TG, Peterson KR, Cunha AF, et al. (2006). "Identification of novel candidate genes for globin regulation in erythroid cells containing large deletions of the human beta-globin gene cluster". Blood Cells Mol. Dis. 37 (2): 82–90. doi:10.1016/j.bcmd.2006.07.003. PMID 16952470.


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