TRIM41

Protein-coding gene in the species Homo sapiens
TRIM41
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

2EGM

Identifiers
AliasesTRIM41, RINCK, tripartite motif containing 41
External IDsOMIM: 610530; MGI: 2384814; HomoloGene: 14140; GeneCards: TRIM41; OMA:TRIM41 - orthologs
Gene location (Human)
Chromosome 5 (human)
Chr.Chromosome 5 (human)[1]
Chromosome 5 (human)
Genomic location for TRIM41
Genomic location for TRIM41
Band5q35.3Start181,222,499 bp[1]
End181,235,808 bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]
Chromosome 11 (mouse)
Genomic location for TRIM41
Genomic location for TRIM41
Band11|11 B1.2Start48,697,231 bp[2]
End48,708,180 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • C1 segment

  • internal globus pallidus

  • inferior ganglion of vagus nerve

  • subthalamic nucleus

  • substantia nigra

  • amygdala

  • medulla oblongata

  • ventral tegmental area

  • skin of arm

  • superior vestibular nucleus
Top expressed in
  • neural layer of retina

  • Rostral migratory stream

  • Paneth cell

  • dentate gyrus of hippocampal formation granule cell

  • Gonadal ridge

  • condyle

  • granulocyte

  • lip

  • fossa

  • medullary collecting duct
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • zinc ion binding
  • protein binding
  • metal ion binding
  • identical protein binding
  • transferase activity
Cellular component
  • cytoplasm
  • nucleolus
  • intracellular anatomical structure
  • nucleus
  • nuclear body
Biological process
  • protein ubiquitination
  • cellular response to lipopolysaccharide
  • cellular response to muramyl dipeptide
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

90933

211007

Ensembl

ENSG00000146063

ENSMUSG00000040365

UniProt

Q8WV44

Q5NCC3

RefSeq (mRNA)

NM_033549
NM_201627

NM_145377

RefSeq (protein)

NP_291027
NP_963921

NP_663352

Location (UCSC)Chr 5: 181.22 – 181.24 MbChr 11: 48.7 – 48.71 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Tripartite motif-containing protein 41 is a protein that in humans is encoded by the TRIM41 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000146063 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040365 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Tanaka M, Fukuda Y, Mashima K, Hanai R (Jul 2005). "Intracellular localization and domain organization of human TRIM41 proteins". Mol Biol Rep. 32 (2): 87–93. doi:10.1007/s11033-004-6613-2. PMID 16022281. S2CID 24151951.
  6. ^ "Entrez Gene: TRIM41 tripartite motif-containing 41".

Further reading

  • Chen D, Gould C, Garza R, et al. (2008). "Amplitude control of protein kinase C by RINCK, a novel E3 ubiquitin ligase". J. Biol. Chem. 282 (46): 33776–87. doi:10.1074/jbc.M703320200. PMID 17893151.
  • Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  • Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. Bibcode:2004PNAS..10115724W. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Kobayashi M, Hanai R (2001). "M phase-specific association of human topoisomerase IIIbeta with chromosomes". Biochem. Biophys. Res. Commun. 287 (1): 282–7. doi:10.1006/bbrc.2001.5580. PMID 11549288.


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