TRAT1 |
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Identifiers |
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Aliases | TRAT1, TCRIM, TRIM, HSPC062, pp29/30, T cell receptor associated transmembrane adaptor 1, T-cell receptor associated transmembrane adaptor 1 |
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External IDs | OMIM: 604962; MGI: 1924897; HomoloGene: 41130; GeneCards: TRAT1; OMA:TRAT1 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 3 (human)[1] |
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| Band | 3q13.13 | Start | 108,822,770 bp[1] |
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End | 108,855,005 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 16 (mouse)[2] |
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| Band | 16|16 B5 | Start | 48,551,137 bp[2] |
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End | 48,592,384 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - thymus
- buccal mucosa cell
- lymph node
- testicle
- blood
- granulocyte
- appendix
- epithelium of nasopharynx
- spleen
- epithelium of colon
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| Top expressed in | - thymus
- blood
- mesenteric lymph nodes
- embryo
- spleen
- subcutaneous adipose tissue
- superior frontal gyrus
- gastrula
- primary visual cortex
- vastus lateralis muscle
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - transmembrane receptor protein tyrosine kinase adaptor activity
- phosphatidylinositol-4,5-bisphosphate 3-kinase activity
| Cellular component | - integral component of membrane
- membrane
- plasma membrane
- integral component of plasma membrane
- T cell receptor complex
| Biological process | - positive regulation of calcium-mediated signaling
- adaptive immune response
- immune system process
- positive regulation of T cell receptor signaling pathway
- negative regulation of transport
- cellular defense response
- T cell receptor signaling pathway
- negative regulation of receptor recycling
- signal transduction
- phosphatidylinositol phosphate biosynthetic process
- transmembrane receptor protein tyrosine kinase signaling pathway
- positive regulation of protein kinase B signaling
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 3: 108.82 – 108.86 Mb | Chr 16: 48.55 – 48.59 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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