TAF1D

Protein-coding gene in the species Homo sapiens
TAF1D
Identifiers
AliasesTAF1D, JOSD3, RAFI41, TAF(I)41, TAFI41, TATA-box binding protein associated factor, RNA polymerase I subunit D
External IDsOMIM: 612823; MGI: 1922566; HomoloGene: 11472; GeneCards: TAF1D; OMA:TAF1D - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for TAF1D
Genomic location for TAF1D
Band11q21Start93,729,948 bp[1]
End93,784,391 bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for TAF1D
Genomic location for TAF1D
Band9|9 A2Start15,306,214 bp[2]
End15,316,991 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • body of pancreas

  • visceral pleura

  • sural nerve

  • primary visual cortex

  • left ovary

  • parietal pleura

  • anterior cingulate cortex

  • right frontal lobe

  • C1 segment

  • pylorus
Top expressed in
  • Ileal epithelium

  • genital tubercle

  • embryo

  • tail of embryo

  • embryo

  • superior surface of tongue

  • morula

  • morula

  • blastocyst

  • ectoderm
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • DNA binding
  • protein binding
Cellular component
  • RNA polymerase transcription factor SL1 complex
  • nucleus
  • nucleoplasm
  • microtubule organizing center
Biological process
  • transcription initiation from RNA polymerase I promoter
  • termination of RNA polymerase I transcription
  • epigenetic maintenance of chromatin in transcription-competent conformation
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • transcription elongation from RNA polymerase I promoter
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

79101

75316

Ensembl

ENSG00000166012

ENSMUSG00000031939

UniProt

Q9H5J8

Q9D4V4

RefSeq (mRNA)

NM_024116

NM_026541
NM_027261
NM_029248

RefSeq (protein)

NP_077021

NP_081537
NP_083524

Location (UCSC)Chr 11: 93.73 – 93.78 MbChr 9: 15.31 – 15.32 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa is a protein that in humans is encoded by the TAF1D gene.[5]

Function

TAF1D is a member of the SL1 complex, which includes TBP and TAF1A, TAF1B, and TAF1C, and plays a role in RNA polymerase I transcription.[6][7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000166012 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031939 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa".
  6. ^ Wang L, Bhattacharyya N, Chelsea DM, Escobar PF, Banerjee S (November 2004). "A novel nuclear protein, MGC5306 interacts with DNA polymerase beta and has a potential role in cellular phenotype". Cancer Research. 64 (21): 7673–7. doi:10.1158/0008-5472.CAN-04-2801. PMID 15520167.
  7. ^ Gorski JJ, Pathak S, Panov K, Kasciukovic T, Panova T, Russell J, Zomerdijk JC (March 2007). "A novel TBP-associated factor of SL1 functions in RNA polymerase I transcription". The EMBO Journal. 26 (6): 1560–8. doi:10.1038/sj.emboj.7601601. PMC 1829371. PMID 17318177.


  • v
  • t
  • e