SYNJ2 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | SYNJ2, INPP5H, synaptojanin 2 |
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External IDs | OMIM: 609410; MGI: 1201671; HomoloGene: 117703; GeneCards: SYNJ2; OMA:SYNJ2 - orthologs |
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Gene location (Human) |
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![Chromosome 6 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/03/Ideogram_human_chromosome_6.svg/300px-Ideogram_human_chromosome_6.svg.png) | Chr. | Chromosome 6 (human)[1] |
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| Band | 6q25.3 | Start | 157,981,863 bp[1] |
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End | 158,099,176 bp[1] |
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Gene location (Mouse) |
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![Chromosome 17 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/1/13/Ideogram_house_mouse_chromosome_17.svg/260px-Ideogram_house_mouse_chromosome_17.svg.png) | Chr. | Chromosome 17 (mouse)[2] |
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| Band | 17 A1|17 3.59 cM | Start | 5,991,555 bp[2] |
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End | 6,094,565 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - inferior ganglion of vagus nerve
- internal globus pallidus
- C1 segment
- subthalamic nucleus
- medulla oblongata
- pons
- superior vestibular nucleus
- corpus callosum
- inferior olivary nucleus
- ventral tegmental area
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| Top expressed in | - muscle of thigh
- spermatid
- primary visual cortex
- dentate gyrus of hippocampal formation granule cell
- ascending aorta
- soleus muscle
- right ventricle
- lumbar subsegment of spinal cord
- superior frontal gyrus
- temporal muscle
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - phosphoric ester hydrolase activity
- protein binding
- hydrolase activity
- RNA binding
- nucleic acid binding
- phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
- phosphatidylinositol phosphate 4-phosphatase activity
- phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
- phosphatidylinositol-3-phosphatase activity
- phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
- phosphatidylinositol phosphate 5-phosphatase activity
- inositol-polyphosphate 5-phosphatase activity
- SH3 domain binding
- PDZ domain binding
- phosphatidylinositol-4-phosphate phosphatase activity
| Cellular component | - cytoplasm
- membrane raft
- axon
- cytosol
- plasma membrane
- cell projection
- cytoskeleton
- membrane
- cytoplasmic microtubule
- extrinsic component of mitochondrial outer membrane
- ruffle membrane
- axon terminus
- perinuclear region of cytoplasm
- presynapse
| Biological process | - phosphatidylinositol biosynthetic process
- phosphatidylinositol dephosphorylation
- phosphatidylinositol-3-phosphate biosynthetic process
- membrane organization
- brain development
- inositol phosphate dephosphorylation
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | NM_001113351 NM_001113352 NM_001113353 NM_001290698 NM_011523
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NM_001357665 NM_001357667 |
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RefSeq (protein) | | NP_001106822 NP_001106823 NP_001106824 NP_001277627 NP_035653
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NP_001344594 NP_001344596 |
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Location (UCSC) | Chr 6: 157.98 – 158.1 Mb | Chr 17: 5.99 – 6.09 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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