RNF38

Protein-coding gene in the species Homo sapiens

RNF38

Available structures

PDB

Ortholog search: PDBe RCSB

List of PDB id codes
1X4J, 4V3K, 4V3L

Identifiers

Aliases

RNF38, ring finger protein 38

External IDs

OMIM: 612488; MGI: 1920719; HomoloGene: 32550; GeneCards: RNF38; OMA:RNF38 - orthologs

Gene location (Human)

Chr.	Chromosome 9 (human)^[1]

Band	9p13.2	Start	36,336,396 bp^[1]
Band	9p13.2	End	36,487,548 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 4 (mouse)^[2]

Band	4\|4 B1	Start	44,126,210 bp^[2]
Band	4\|4 B1	End	44,233,789 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

sperm

secondary oocyte

left testis

right testis

ganglionic eminence

tail of epididymis

metanephric glomerulus

germinal epithelium

Epithelium of choroid plexus

Brodmann area 23

Top expressed in

zygote

secondary oocyte

seminiferous tubule

primary oocyte

aortic valve

ascending aorta

genital tubercle

tail of embryo

blood

ganglionic eminence

More reference expression data

BioGPS


More reference expression data

Gene ontology
Molecular function	metal ion binding ubiquitin-protein transferase activity ubiquitin protein ligase activity transferase activity
Cellular component	sperm flagellum nucleus nucleoplasm
Biological process	male gonad development protein ubiquitination proteasome-mediated ubiquitin-dependent protein catabolic process
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


152006


73469

Ensembl


ENSG00000137075


ENSMUSG00000035696

UniProt


Q9H0F5


Q8BI21

RefSeq (mRNA)

NM_022781 NM_194328 NM_194329 NM_194330 NM_194331
NM_194332

NM_001038993 NM_175201 NM_001355181 NM_001379574 NM_001379575
NM_001379576 NM_001379577 NM_001379578 NM_001379579 NM_001379580 NM_001379581

RefSeq (protein)


NP_073618 NP_919309 NP_919310 NP_919311 NP_919313

NP_001034082 NP_780410 NP_001342110 NP_001366503 NP_001366504
NP_001366505 NP_001366506 NP_001366507 NP_001366508 NP_001366509 NP_001366510

Location (UCSC)

Chr 9: 36.34 – 36.49 Mb

Chr 4: 44.13 – 44.23 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

RING finger protein 38 is a protein that in humans is encoded by the RNF38 gene.^[5]

This gene encodes a protein with a coiled-coil motif and a RING-H2 motif (C3H2C2) at its carboxy-terminus. The RING motif is a zinc-binding domain found in a large set of proteins playing roles in diverse cellular processes including oncogenesis, development, signal transduction, and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000137075 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035696 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: RNF38 ring finger protein 38".

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