Protein-coding gene in the species Homo sapiens
RBP7 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | RBP7, CRBP4, CRBPIV, retinol binding protein 7, CRABP4 |
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External IDs | OMIM: 608604; MGI: 1890409; HomoloGene: 32521; GeneCards: RBP7; OMA:RBP7 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 1 (human)[1] |
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| Band | 1p36.22 | Start | 9,997,206 bp[1] |
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End | 10,016,021 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 4 (mouse)[2] |
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| Band | 4|4 E2 | Start | 149,534,144 bp[2] |
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End | 149,539,435 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - abdominal fat
- pericardium
- subcutaneous adipose tissue
- monocyte
- spleen
- apex of heart
- granulocyte
- vena cava
- gastric mucosa
- tendon of biceps brachii
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| Top expressed in | - interventricular septum
- soleus muscle
- brown adipose tissue
- white adipose tissue
- myocardium of ventricle
- muscle of thigh
- right ventricle
- subcutaneous adipose tissue
- intercostal muscle
- left ventricle
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - retinol binding
- protein binding
- retinoid binding
- retinal binding
- lipid binding
| Cellular component | | Biological process | | Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 1: 10 – 10.02 Mb | Chr 4: 149.53 – 149.54 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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Retinol binding protein 7 is a protein that in humans is encoded by the RBP7 gene. [5]
Function
The protein encoded by this gene is a member of the cellular retinol-binding protein (CRBP) family, whose members are required for vitamin A stability and metabolism. The encoded protein binds all-trans-retinol and is structurally similar to other CRBPs; however, it has a lower binding affinity for retinol than other CRBPs. [provided by RefSeq, Aug 2016].
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000162444 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028996 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Retinol binding protein 7". Retrieved 2018-01-11.
External links
- PDBe-KB provides an overview of all the structure information available in the PDB for Human Retinoid-binding protein 7
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.