RBM19

Protein-coding gene in the species Homo sapiens

RBM19
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

2DGW

Identifiers
AliasesRBM19, RNA binding motif protein 19, Mrd1
External IDsOMIM: 616444; MGI: 1921361; HomoloGene: 7158; GeneCards: RBM19; OMA:RBM19 - orthologs
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for RBM19
Genomic location for RBM19
Band12q24.13-q24.21Start113,816,738 bp[1]
End113,966,325 bp[1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr.Chromosome 5 (mouse)[2]
Chromosome 5 (mouse)
Genomic location for RBM19
Genomic location for RBM19
Band5|5 FStart120,254,530 bp[2]
End120,337,046 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • sural nerve

  • left lobe of thyroid gland

  • right lobe of thyroid gland

  • right uterine tube

  • left ovary

  • apex of heart

  • right ovary

  • left adrenal cortex

  • right adrenal cortex

  • body of uterus
Top expressed in
  • yolk sac

  • tail of embryo

  • interventricular septum

  • zygote

  • genital tubercle

  • epiblast

  • spermatocyte

  • morula

  • internal carotid artery

  • embryo
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • nucleic acid binding
  • RNA binding
Cellular component
  • cytoplasm
  • nucleolus
  • membrane
  • nucleoplasm
  • chromosome
  • nucleus
  • nuclear speck
Biological process
  • multicellular organism development
  • positive regulation of embryonic development
  • regulation of alternative mRNA splicing, via spliceosome
  • mRNA cis splicing, via spliceosome
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

9904

74111

Ensembl

ENSG00000122965

ENSMUSG00000029594

UniProt

Q9Y4C8

Q8R3C6

RefSeq (mRNA)

NM_001146698
NM_001146699
NM_016196

NM_028762

RefSeq (protein)

NP_001140170
NP_001140171
NP_057280

NP_083038

Location (UCSC)Chr 12: 113.82 – 113.97 MbChr 5: 120.25 – 120.34 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Probable RNA-binding protein 19 is a protein that in humans is encoded by the RBM19 gene.[5][6][7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000122965 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029594 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Ishikawa K, Nagase T, Suyama M, et al. (Dec 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.
  6. ^ Wiemann S, Weil B, Wellenreuther R, et al. (Mar 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  7. ^ "Entrez Gene: RBM19 RNA binding motif protein 19".

Further reading

  • Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
  • Scherl A, Couté Y, Déon C, et al. (2003). "Functional Proteomic Analysis of Human Nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Mayer AN, Fishman MC (2003). "Nil per os encodes a conserved RNA recognition motif protein required for morphogenesis and cytodifferentiation of digestive organs in zebrafish". Development. 130 (17): 3917–28. doi:10.1242/dev.00600. PMID 12874115.
  • Colland F, Jacq X, Trouplin V, et al. (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
  • v
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  • 2cpf: Solution structure of the penultimate RNA recognition motif of hypothetical RNA-binding protein RBM19
    2cpf: Solution structure of the penultimate RNA recognition motif of hypothetical RNA-binding protein RBM19
  • 2cph: Solution structure of the C-terminal RNA recognition motif of hypothetical RNA-binding protein RBM19
    2cph: Solution structure of the C-terminal RNA recognition motif of hypothetical RNA-binding protein RBM19
  • 2dgw: Solution structure of the second RNA recognition motif in RNA-binding protein 19
    2dgw: Solution structure of the second RNA recognition motif in RNA-binding protein 19


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