Peruvoside

Chemical compound
  • C01AX02 (WHO)
Identifiers
  • (3β,5β,8ξ,9ξ)- 3-[(6-deoxy- 3-O-methyl- α-D- glycero- hexopyranosyl)oxy]- 14-hydroxy- 19-oxocard- 20(22)enolide
CAS Number
  • 1182-87-2 ☒N
PubChem CID
  • 14449
ChemSpider
  • 16498835 checkY
UNII
  • CT36KGC6A6
ChEMBL
  • ChEMBL1075790 checkY
CompTox Dashboard (EPA)
  • DTXSID70881388 Edit this at Wikidata
ECHA InfoCard100.013.327 Edit this at WikidataChemical and physical dataFormulaC30H44O9Molar mass548.673 g·mol−13D model (JSmol)
  • Interactive image
  • O=C\1OC/C(=C/1)[C@H]6CC[C@@]5(O)[C@]6(C)CC[C@H]3[C@H]5CC[C@@H]4C[C@@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](OC)[C@@H]2O)CC[C@]34C=O
InChI
  • InChI=1S/C30H44O9/c1-16-24(33)26(36-3)25(34)27(38-16)39-19-6-10-29(15-31)18(13-19)4-5-22-21(29)7-9-28(2)20(8-11-30(22,28)35)17-12-23(32)37-14-17/h12,15-16,18-22,24-27,33-35H,4-11,13-14H2,1-3H3/t16-,18+,19-,20+,21-,22+,24-,25-,26+,27-,28+,29+,30-/m0/s1 checkY
  • Key:PMTSPAGBAFCORP-HBUONDEYSA-N checkY

Peruvoside (or cannogenin thevetoside) is a cardiac glycoside[1] for heart failure.[2]

It is derived from Cascabela thevetia (Thevetia neriifolia).[2]

References

  1. ^ Arora RB, Rangaswami S (1972). Peruvoside and Other Cardiotonic Glycoside[s] of Thevetia neriifolia Juss: Chemical, Pharmacological, and Clinical Studies. New Delhi, India: Thomson. LCCN 78900408.
  2. ^ a b Bhatia ML, Manchanda SC, Roy SB (September 1970). "Haemodynamic studies with peruvoside in human congestive heart failure". British Medical Journal. 3 (5725): 740–3. doi:10.1136/bmj.3.5725.740. PMC 1701679. PMID 4919553.
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