PGAM5 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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3MXO, 3O0T |
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Identifiers |
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Aliases | PGAM5, BXLBV68, PGAM family member 5, mitochondrial serine/threonine protein phosphatase |
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External IDs | OMIM: 614939; MGI: 1919792; HomoloGene: 14597; GeneCards: PGAM5; OMA:PGAM5 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 12 (human)[1] |
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| Band | 12q24.33 | Start | 132,710,819 bp[1] |
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End | 132,722,734 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 5 (mouse)[2] |
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| Band | 5|5 F | Start | 110,406,996 bp[2] |
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End | 110,417,779 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - gastrocnemius muscle
- mucosa of transverse colon
- muscle of thigh
- right adrenal gland
- islet of Langerhans
- right lobe of liver
- appendix
- left adrenal gland
- right adrenal cortex
- left adrenal cortex
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| Top expressed in | - superior cervical ganglion
- endocardial cushion
- interventricular septum
- mandibular prominence
- neural tube
- medial ganglionic eminence
- barrel cortex
- maxillary prominence
- piriform cortex
- subiculum
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - phosphatase activity
- phosphoprotein phosphatase activity
- hydrolase activity
- GTPase activator activity
- protein binding
- protein-containing complex binding
- protein serine/threonine phosphatase activity
| Cellular component | - integral component of membrane
- membrane
- mitochondrion
- mitochondrial outer membrane
| Biological process | - protein dephosphorylation
- necroptosis
- programmed cell death
- dephosphorylation
- positive regulation of GTPase activity
- macroautophagy
- negative regulation of cold-induced thermogenesis
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_138575 NM_001170543 NM_001170544 |
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RefSeq (protein) | |
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NP_001164014 NP_001164015 NP_612642 |
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Location (UCSC) | Chr 12: 132.71 – 132.72 Mb | Chr 5: 110.41 – 110.42 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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