PCGF5

Protein-coding gene in the species Homo sapiens
PCGF5
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

4S3O

Identifiers
AliasesPCGF5, RNF159, polycomb group ring finger 5
External IDsOMIM: 617407; MGI: 1923505; HomoloGene: 12632; GeneCards: PCGF5; OMA:PCGF5 - orthologs
Gene location (Human)
Chromosome 10 (human)
Chr.Chromosome 10 (human)[1]
Chromosome 10 (human)
Genomic location for PCGF5
Genomic location for PCGF5
Band10q23.32Start91,163,012 bp[1]
End91,284,337 bp[1]
Gene location (Mouse)
Chromosome 19 (mouse)
Chr.Chromosome 19 (mouse)[2]
Chromosome 19 (mouse)
Genomic location for PCGF5
Genomic location for PCGF5
Band19|19 C2Start36,325,709 bp[2]
End36,438,370 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • cardiac muscle tissue of right atrium

  • myocardium of left ventricle

  • blood

  • Pars compacta

  • skin of arm

  • superior vestibular nucleus

  • saphenous vein

  • pars reticulata

  • monocyte

  • oocyte
Top expressed in
  • spermatocyte

  • ascending aorta

  • aortic valve

  • otolith organ

  • utricle

  • seminiferous tubule

  • atrioventricular valve

  • knee joint

  • ciliary body

  • spermatid
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein binding
  • metal ion binding
  • RNA polymerase II transcription regulatory region sequence-specific DNA binding
  • DNA-binding transcription factor activity
Cellular component
  • centrosome
  • nucleolus
  • nucleus
  • nucleoplasm
  • X chromosome
  • PcG protein complex
  • PRC1 complex
Biological process
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • positive regulation of transcription by RNA polymerase II
  • histone H2A-K119 monoubiquitination
  • inactivation of X chromosome by genetic imprinting
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

84333

76073

Ensembl

ENSG00000180628

ENSMUSG00000024805

UniProt

Q86SE9

Q3UK78

RefSeq (mRNA)

NM_001256549
NM_001257101
NM_032373

NM_029508
NM_001368690
NM_001368691
NM_001368692
NM_001368693

RefSeq (protein)

NP_001243478
NP_001244030
NP_115749

NP_083784
NP_001355619
NP_001355620
NP_001355621
NP_001355622

Location (UCSC)Chr 10: 91.16 – 91.28 MbChr 19: 36.33 – 36.44 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Polycomb group RING finger protein 5 is a protein that in humans is encoded by the PCGF5 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000180628 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024805 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Matoba R, Okubo K, Hori N, Fukushima A, Matsubara K (Oct 1994). "The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression". Gene. 146 (2): 199–207. doi:10.1016/0378-1119(94)90293-3. PMID 8076819.
  6. ^ "Entrez Gene: PCGF5 polycomb group ring finger 5".

Further reading

  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.


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