Protein-coding gene in the species Homo sapiens
OR6C1 |
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Identifiers |
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Aliases | OR6C1, OST267, olfactory receptor family 6 subfamily C member 1 |
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External IDs | MGI: 3030636; HomoloGene: 105151; GeneCards: OR6C1; OMA:OR6C1 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 12 (human)[1] |
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| Band | 12q13.2 | Start | 55,314,343 bp[1] |
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End | 55,322,364 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 10 (mouse)[2] |
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| Band | 10|10 D3 | Start | 129,513,552 bp[2] |
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End | 129,524,038 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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| | More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - G protein-coupled receptor activity
- olfactory receptor activity
- signal transducer activity
| Cellular component | - integral component of membrane
- plasma membrane
- membrane
| Biological process | - sensory perception of smell
- detection of chemical stimulus involved in sensory perception of smell
- signal transduction
- response to stimulus
- G protein-coupled receptor signaling pathway
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 12: 55.31 – 55.32 Mb | Chr 10: 129.51 – 129.52 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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Olfactory receptor 6C1 is a protein that in humans is encoded by the OR6C1 gene.[5]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]
See also
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000205330 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000093866 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b "Entrez Gene: OR6C1 olfactory receptor, family 6, subfamily C, member 1".
Further reading
- Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes" (PDF). Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
- Scherer SE, Muzny DM, Buhay CJ, et al. (2006). "The finished DNA sequence of human chromosome 12". Nature. 440 (7082): 346–51. Bibcode:2006Natur.440..346S. doi:10.1038/nature04569. PMID 16541075.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.