NPNT |
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Identifiers |
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Aliases | NPNT, EGFL6L, POEM, nephronectin |
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External IDs | OMIM: 610306; MGI: 2148811; HomoloGene: 14138; GeneCards: NPNT; OMA:NPNT - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 4 (human)[1] |
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| Band | 4q24 | Start | 105,894,775 bp[1] |
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End | 106,004,027 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 3 (mouse)[2] |
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| Band | 3|3 G3 | Start | 132,587,506 bp[2] |
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End | 132,656,052 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - right lobe of thyroid gland
- left lobe of thyroid gland
- right lung
- jejunal mucosa
- right coronary artery
- Descending thoracic aorta
- ascending aorta
- lower lobe of lung
- upper lobe of lung
- upper lobe of left lung
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| Top expressed in | - ascending aorta
- epithelium of lens
- aortic valve
- left lung lobe
- tunica media of zone of aorta
- right lung lobe
- calvaria
- medullary collecting duct
- molar
- efferent ductule
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - calcium ion binding
- integrin binding
- extracellular matrix structural constituent
| Cellular component | - membrane
- smooth muscle contractile fiber
- extracellular matrix
- integrin alpha8-beta1 complex
- extracellular region
- basement membrane
- extracellular exosome
- extracellular space
- collagen-containing extracellular matrix
| Biological process | - positive regulation of transforming growth factor beta receptor signaling pathway
- cell differentiation
- ureteric bud development
- establishment of protein localization
- cellular response to tumor necrosis factor
- extracellular matrix organization
- cell-cell adhesion mediated by integrin
- multicellular organism development
- branching involved in ureteric bud morphogenesis
- positive regulation of osteoblast differentiation
- cell adhesion
- pilomotor reflex
- positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
- positive regulation of alkaline phosphatase activity
- positive regulation of ERK1 and ERK2 cascade
- cell-matrix adhesion
- positive regulation of smooth muscle contraction
- positive regulation of cell-substrate adhesion
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001033047 NM_001184690 NM_001184691 NM_001184692 NM_001184693
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NM_198278 |
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NM_001029836 NM_001287101 NM_001287102 NM_001287103 NM_033525 |
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RefSeq (protein) | |
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NP_001028219 NP_001171619 NP_001171620 NP_001171621 NP_001171622 |
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NP_001025007 NP_001274030 NP_001274031 NP_001274032 NP_277060 |
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Location (UCSC) | Chr 4: 105.89 – 106 Mb | Chr 3: 132.59 – 132.66 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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