NSD1 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | NSD1, ARA267, KMT3B, SOTOS, SOTOS1, STO, nuclear receptor binding SET domain protein 1 |
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External IDs | OMIM: 606681; MGI: 1276545; HomoloGene: 32543; GeneCards: NSD1; OMA:NSD1 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 5 (human)[1] |
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| Band | 5q35.3 | Start | 177,131,830 bp[1] |
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End | 177,300,213 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 13 (mouse)[2] |
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| Band | 13|13 B1 | Start | 55,357,595 bp[2] |
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End | 55,466,138 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - sural nerve
- epithelium of colon
- Achilles tendon
- ventricular zone
- testicle
- ganglionic eminence
- monocyte
- sperm
- tonsil
- corpus callosum
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| Top expressed in | - ascending aorta
- aortic valve
- genital tubercle
- tail of embryo
- Rostral migratory stream
- pineal gland
- supraoptic nucleus
- vas deferens
- ventricular zone
- mesenteric lymph nodes
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - methyltransferase activity
- transferase activity
- histone methyltransferase activity (H4-K20 specific)
- transcription corepressor activity
- chromatin binding
- transcription coregulator activity
- metal ion binding
- retinoid X receptor binding
- thyroid hormone receptor binding
- androgen receptor binding
- retinoic acid receptor binding
- estrogen receptor binding
- histone-lysine N-methyltransferase activity
- histone methyltransferase activity (H3-K36 specific)
- zinc ion binding
- protein binding
- RNA polymerase II cis-regulatory region sequence-specific DNA binding
| Cellular component | - nucleoplasm
- chromosome
- nucleus
- chromatin
| Biological process | - regulation of transcription, DNA-templated
- negative regulation of transcription by RNA polymerase II
- transcription, DNA-templated
- positive regulation of transcription, DNA-templated
- methylation
- regulation of peptidyl-serine phosphorylation
- regulation of histone H3-K36 methylation
- histone lysine methylation
- histone methylation
- regulation of RNA polymerase II regulatory region sequence-specific DNA binding
- histone H3-K36 methylation
- histone H4-K20 methylation
- chromatin organization
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_022455 NM_172349 NM_001365684 |
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RefSeq (protein) | |
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NP_071900 NP_758859 NP_001352613 |
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Location (UCSC) | Chr 5: 177.13 – 177.3 Mb | Chr 13: 55.36 – 55.47 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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