NRSN1

Protein-coding gene in the species Homo sapiens
NRSN1
Identifiers
AliasesNRSN1, VMP, p24, neurensin 1
External IDsOMIM: 616630; MGI: 894662; HomoloGene: 7597; GeneCards: NRSN1; OMA:NRSN1 - orthologs
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for NRSN1
Genomic location for NRSN1
Band6p22.3Start24,126,186 bp[1]
End24,154,900 bp[1]
Gene location (Mouse)
Chromosome 13 (mouse)
Chr.Chromosome 13 (mouse)[2]
Chromosome 13 (mouse)
Genomic location for NRSN1
Genomic location for NRSN1
Band13|13 A3.1Start25,436,023 bp[2]
End25,454,485 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • dorsolateral prefrontal cortex

  • cingulate gyrus

  • anterior cingulate cortex

  • Brodmann area 9

  • prefrontal cortex

  • nucleus accumbens

  • Brodmann area 46

  • right frontal lobe

  • hypothalamus

  • amygdala
Top expressed in
  • primary visual cortex

  • cingulate gyrus

  • superior frontal gyrus

  • medial vestibular nucleus

  • mammillary body

  • Region I of hippocampus proper

  • primary motor cortex

  • dentate gyrus of hippocampal formation granule cell

  • deep cerebellar nuclei

  • pontine nuclei
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein binding
Cellular component
  • growth cone
  • transport vesicle
  • membrane
  • integral component of membrane
  • neuronal cell body
  • neuron projection
  • cytoplasmic vesicle
Biological process
  • nervous system development
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

140767

22360

Ensembl

ENSG00000152954

ENSMUSG00000048978

UniProt

Q8IZ57

P97799

RefSeq (mRNA)

NM_080723

NM_009513

RefSeq (protein)

NP_542454

NP_033539

Location (UCSC)Chr 6: 24.13 – 24.15 MbChr 13: 25.44 – 25.45 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Neurensin-1 is a protein that in humans is encoded by the NRSN1 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000152954 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000048978 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Cheng C, Xu J, Ye X, Dai J, Wu Q, Zeng L, Wang L, Zhao W, Ji C, Gu S, Xie Y, Mao Y (Dec 2002). "Cloning, expression and characterization of a novel human VMP gene". Mol Biol Rep. 29 (3): 281–6. doi:10.1023/A:1020402410522. PMID 12463420. S2CID 21283094.
  6. ^ "Entrez Gene: NRSN1 neurensin 1".

Further reading

  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Hecht HJ, Szardenings M, Collins J, Schomburg D (1991). "Three-dimensional structure of the complexes between bovine chymotrypsinogen A and two recombinant variants of human pancreatic secretory trypsin inhibitor (Kazal-type)". J. Mol. Biol. 220 (3): 711–22. doi:10.1016/0022-2836(91)90112-J. PMID 1870127.


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