LPCAT1 |
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Identifiers |
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Aliases | LPCAT1, lysophosphatidylcholine acyltransferase 1, AYTL2, PFAAP3, lpcat, AGPAT10, AGPAT9, LPCAT-1, lysoPAFAT |
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External IDs | OMIM: 610472; MGI: 2384812; HomoloGene: 9871; GeneCards: LPCAT1; OMA:LPCAT1 - orthologs |
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EC number | 2.3.1.67 |
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Gene location (Human) |
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| Chr. | Chromosome 5 (human)[1] |
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| Band | 5p15.33 | Start | 1,456,480 bp[1] |
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End | 1,523,962 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 13 (mouse)[2] |
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| Band | 13|13 C1 | Start | 73,615,316 bp[2] |
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End | 73,664,541 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - upper lobe of left lung
- spleen
- ventricular zone
- granulocyte
- right lung
- ganglionic eminence
- blood
- lymph node
- monocyte
- appendix
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| Top expressed in | - left lung
- left lung lobe
- Rostral migratory stream
- right lung
- right lung lobe
- retinal pigment epithelium
- tibiofemoral joint
- ciliary body
- primary oocyte
- fetal liver hematopoietic progenitor cell
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - 1-alkylglycerophosphocholine O-acyltransferase activity
- metal ion binding
- calcium ion binding
- transferase activity
- acyltransferase activity
- 1-alkylglycerophosphocholine O-acetyltransferase activity
- 1-alkenylglycerophosphocholine O-acyltransferase activity
- 1-acylglycerophosphocholine O-acyltransferase activity
- 1-acylglycerol-3-phosphate O-acyltransferase activity
- 2-acylglycerol-3-phosphate O-acyltransferase activity
| Cellular component | - integral component of membrane
- Golgi apparatus
- Golgi membrane
- membrane
- lipid droplet
- endoplasmic reticulum membrane
- endoplasmic reticulum
- plasma membrane
- azurophil granule membrane
| Biological process | - phospholipid biosynthetic process
- retina development in camera-type eye
- lipid metabolism
- phosphatidylglycerol acyl-chain remodeling
- positive regulation of protein catabolic process
- phosphatidic acid biosynthetic process
- metabolism
- surfactant homeostasis
- negative regulation of phosphatidylcholine biosynthetic process
- phosphatidylcholine acyl-chain remodeling
- phospholipid metabolic process
- phosphatidylcholine biosynthetic process
- neutrophil degranulation
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | |
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ENSG00000275079 ENSG00000153395 |
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UniProt | | |
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RefSeq (mRNA) | | |
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NM_145376 NM_001368681 NM_001368682 |
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RefSeq (protein) | | |
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NP_663351 NP_001355610 NP_001355611 |
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Location (UCSC) | Chr 5: 1.46 – 1.52 Mb | Chr 13: 73.62 – 73.66 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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