HOOK3 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | HOOK3, HK3, hook microtubule-tethering protein 3, hook microtubule tethering protein 3 |
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External IDs | OMIM: 607825; MGI: 2443554; HomoloGene: 13022; GeneCards: HOOK3; OMA:HOOK3 - orthologs |
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Gene location (Human) |
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![Chromosome 8 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/6/60/Ideogram_human_chromosome_8.svg/300px-Ideogram_human_chromosome_8.svg.png) | Chr. | Chromosome 8 (human)[1] |
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| Band | 8p11.21 | Start | 42,896,946 bp[1] |
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End | 43,030,535 bp[1] |
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Gene location (Mouse) |
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![Chromosome 8 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/1/1f/Ideogram_house_mouse_chromosome_8.svg/260px-Ideogram_house_mouse_chromosome_8.svg.png) | Chr. | Chromosome 8 (mouse)[2] |
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| Band | 8|8 A2 | Start | 26,511,449 bp[2] |
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End | 26,609,252 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - Achilles tendon
- sural nerve
- tendon of biceps brachii
- epithelium of colon
- pancreatic epithelial cell
- corpus callosum
- endothelial cell
- buccal mucosa cell
- internal globus pallidus
- deltoid muscle
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| Top expressed in | - otolith organ
- utricle
- knee joint
- tibialis anterior muscle
- hand
- triceps brachii muscle
- vastus lateralis muscle
- Rostral migratory stream
- tail of embryo
- foot
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - microtubule binding
- protein binding
- identical protein binding
- dynein light intermediate chain binding
- dynactin binding
- dynein light chain binding
- dynein intermediate chain binding
| Cellular component | - HOPS complex
- FHF complex
- cis-Golgi network
- centriolar satellite
- microtubule
- cytoskeleton
- cytosol
- pericentriolar material
- cytoplasm
- Golgi apparatus
- centrosome
| Biological process | - endosome to lysosome transport
- endosome organization
- neuronal stem cell population maintenance
- Golgi localization
- early endosome to late endosome transport
- cytoplasmic microtubule organization
- protein transport
- lysosome organization
- microtubule anchoring at centrosome
- interkinetic nuclear migration
- negative regulation of neurogenesis
- protein localization to centrosome
- cytoskeleton-dependent intracellular transport
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 8: 42.9 – 43.03 Mb | Chr 8: 26.51 – 26.61 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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