MACROH2A2 |
---|
|
Available structures |
---|
PDB | Ortholog search: PDBe RCSB |
---|
|
|
Identifiers |
---|
Aliases | MACROH2A2, macroH2A2, H2A histone family member Y2, H2AFY2, macroH2A.2 histone |
---|
External IDs | OMIM: 616141; MGI: 3037658; HomoloGene: 10246; GeneCards: MACROH2A2; OMA:MACROH2A2 - orthologs |
---|
Gene location (Human) |
---|
| Chr. | Chromosome 10 (human)[1] |
---|
| Band | 10q22.1 | Start | 70,052,544 bp[1] |
---|
End | 70,112,282 bp[1] |
---|
|
Gene location (Mouse) |
---|
| Chr. | Chromosome 10 (mouse)[2] |
---|
| Band | 10|10 B4 | Start | 61,574,444 bp[2] |
---|
End | 61,619,926 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - ganglionic eminence
- ventricular zone
- epithelium of colon
- gingival epithelium
- cerebellar vermis
- pancreatic epithelial cell
- islet of Langerhans
- epithelium of esophagus
- hair follicle
- cerebellar hemisphere
|
| Top expressed in | - genital tubercle
- tail of embryo
- neural tube
- ventricular zone
- maxillary prominence
- ganglionic eminence
- mandibular prominence
- medial ganglionic eminence
- otic placode
- abdominal wall
|
| More reference expression data |
|
---|
BioGPS | | More reference expression data |
|
---|
|
Gene ontology |
---|
Molecular function | - DNA binding
- RNA polymerase II transcription regulatory region sequence-specific DNA binding
- protein heterodimerization activity
- chromatin DNA binding
| Cellular component | - ESC/E(Z) complex
- nucleoplasm
- chromosome
- nucleosome
- chromatin
- extracellular exosome
- Barr body
- nucleus
| Biological process | - nucleosome assembly
- negative regulation of transcription of nucleolar large rRNA by RNA polymerase I
- positive regulation of keratinocyte differentiation
- dosage compensation
- negative regulation of transcription by RNA polymerase II
- establishment of protein localization to chromatin
- brain development
- negative regulation of gene expression, epigenetic
- regulation of cell growth
- chromatin organization
| Sources:Amigo / QuickGO |
|
Orthologs |
---|
Species | Human | Mouse |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (mRNA) | | |
---|
RefSeq (protein) | | |
---|
Location (UCSC) | Chr 10: 70.05 – 70.11 Mb | Chr 10: 61.57 – 61.62 Mb |
---|
PubMed search | [3] | [4] |
---|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|