GSDMC

Protein-coding gene in the species Homo sapiens
GSDMC
Identifiers
AliasesGSDMC, MLZE, gasdermin C
External IDsOMIM: 608384; MGI: 2146102; HomoloGene: 69487; GeneCards: GSDMC; OMA:GSDMC - orthologs
Gene location (Mouse)
Chromosome 15 (mouse)
Chr.Chromosome 15 (mouse)[1]
Chromosome 15 (mouse)
Genomic location for GSDMC
Genomic location for GSDMC
Band15|15 D1Start63,696,195 bp[1]
End63,717,026 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • zone of skin

  • skin of abdomen

  • spleen

  • vagina

  • skeletal muscle tissue

  • minor salivary glands

  • gastrocnemius muscle

  • left ventricle

  • thymus

  • urinary bladder
Top expressed in
  • medullary collecting duct

  • transitional epithelium of urinary bladder

  • left colon

  • zygote

  • crypt of lieberkuhn

  • secondary oocyte

  • crypt of lieberkuhn of small intestine

  • jejunum

  • primary oocyte

  • stomach
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • molecular function
  • phosphatidylserine binding
  • phosphatidylinositol-4,5-bisphosphate binding
  • phosphatidylinositol-4-phosphate binding
Cellular component
  • cytoplasm
  • mitochondrion
  • microtubule organizing center
  • cytosol
  • plasma membrane
  • membrane
Biological process
  • programmed cell death
  • biological process
  • pyroptosis
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

56169

331063

Ensembl

n/a

ENSMUSG00000056293

UniProt

Q9BYG8

Q2KHK6

RefSeq (mRNA)

NM_031415

NM_001168274
NM_177912

RefSeq (protein)

NP_113603

NP_001161746
NP_808580

Location (UCSC)n/aChr 15: 63.7 – 63.72 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Gasdermin C is a protein that in humans is encoded by the GSDMC gene. [4]

References

  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000056293 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Entrez Gene: Gasdermin C". Retrieved 2016-08-26.

Further reading

  • Saeki N, Usui T, Aoyagi K, Kim DH, Sato M, Mabuchi T, Yanagihara K, Ogawa K, Sakamoto H, Yoshida T, Sasaki H (2009). "Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium". Genes Chromosomes Cancer. 48 (3): 261–71. doi:10.1002/gcc.20636. PMID 19051310. S2CID 19705164.


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