GLRX3 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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2DIY, 2WZ9, 2YAN, 3ZYW |
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Identifiers |
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Aliases | GLRX3, GLRX4, GRX3, GRX4, PICOT, TXNL2, TXNL3, glutaredoxin 3 |
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External IDs | OMIM: 612754; MGI: 1353653; HomoloGene: 4769; GeneCards: GLRX3; OMA:GLRX3 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 10 (human)[1] |
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| Band | 10q26.3 | Start | 130,136,391 bp[1] |
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End | 130,184,521 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 7 (mouse)[2] |
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| Band | 7|7 F4 | Start | 137,039,343 bp[2] |
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End | 137,070,323 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - buccal mucosa cell
- islet of Langerhans
- right testis
- left testis
- mucosa of esophagus
- right adrenal gland
- right adrenal cortex
- left adrenal gland
- left adrenal cortex
- body of pancreas
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| Top expressed in | - spermatid
- Ileal epithelium
- spermatocyte
- choroid plexus of fourth ventricle
- lactiferous gland
- yolk sac
- cardiac muscle tissue of left ventricle
- ventricular zone
- embryo
- genital tubercle
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - protein-disulfide reductase activity
- electron transfer activity
- iron-sulfur cluster binding
- protein binding
- metal ion binding
- protein kinase C binding
- RNA binding
- identical protein binding
- glutathione disulfide oxidoreductase activity
| Cellular component | - cytoplasm
- dendrite
- cell cortex
- Z discdkac
- extracellular exosome
- nucleus
- cytosol
| Biological process | - cell redox homeostasis
- negative regulation of cardiac muscle hypertrophy
- regulation of the force of heart contraction
- [2Fe-2S cluster assembly]
- protein maturation by iron-sulfur cluster transfer
- electron transport chain
- cellular iron ion homeostasis
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001199868 NM_006541 NM_001321980 |
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RefSeq (protein) | |
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NP_001186797 NP_001308909 NP_006532 |
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Location (UCSC) | Chr 10: 130.14 – 130.18 Mb | Chr 7: 137.04 – 137.07 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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