GLRA2 |
---|
|
Identifiers |
---|
Aliases | GLRA2, GLR, glycine receptor alpha 2, MRXSP |
---|
External IDs | OMIM: 305990; MGI: 95748; HomoloGene: 31070; GeneCards: GLRA2; OMA:GLRA2 - orthologs |
---|
Gene location (Human) |
---|
| Chr. | X chromosome (human)[1] |
---|
| Band | Xp22.2 | Start | 14,529,298 bp[1] |
---|
End | 14,731,812 bp[1] |
---|
|
Gene location (Mouse) |
---|
| Chr. | X chromosome (mouse)[2] |
---|
| Band | X F5|X 76.75 cM | Start | 163,912,013 bp[2] |
---|
End | 164,110,389 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - testicle
- ganglionic eminence
- cerebellar hemisphere
- right hemisphere of cerebellum
- hypothalamus
- prefrontal cortex
- ventricular zone
- rectum
- cingulate gyrus
- anterior cingulate cortex
|
| Top expressed in | - lumbar subsegment of spinal cord
- ventral tegmental area
- lateral hypothalamus
- lateral septal nucleus
- anterior amygdaloid area
- paraventricular nucleus of hypothalamus
- nucleus of stria terminalis
- nucleus accumbens
- substantia nigra
- dorsomedial hypothalamic nucleus
|
| More reference expression data |
|
---|
BioGPS | | More reference expression data |
|
---|
|
Gene ontology |
---|
Molecular function | - metal ion binding
- glycine binding
- transmitter-gated ion channel activity
- chloride channel activity
- glycine-gated chloride ion channel activity
- extracellularly glycine-gated chloride channel activity
- extracellular ligand-gated ion channel activity
- ion channel activity
- transmembrane signaling receptor activity
- transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
| Cellular component | - synapse
- integral component of membrane
- cell projection
- cell junction
- integral component of plasma membrane
- postsynaptic membrane
- membrane
- chloride channel complex
- plasma membrane
- neuron projection
- glycinergic synapse
| Biological process | - neuropeptide signaling pathway
- chloride transmembrane transport
- chloride transport
- ion transport
- cellular response to amino acid stimulus
- synaptic transmission, glycinergic
- cellular response to ethanol
- cellular response to zinc ion
- excitatory postsynaptic potential
- ion transmembrane transport
- signal transduction
- chemical synaptic transmission
- regulation of membrane potential
- response to amino acid
- nervous system process
- regulation of postsynaptic membrane potential
| Sources:Amigo / QuickGO |
|
Orthologs |
---|
Species | Human | Mouse |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (mRNA) | |
---|
NM_001118885 NM_001118886 NM_001171942 NM_002063 |
| |
---|
NM_183427 NM_001357099 NM_001357100 |
|
---|
RefSeq (protein) | |
---|
NP_001112357 NP_001112358 NP_001165413 NP_002054 |
| |
---|
NP_906272 NP_001344028 NP_001344029 |
|
---|
Location (UCSC) | Chr X: 14.53 – 14.73 Mb | Chr X: 163.91 – 164.11 Mb |
---|
PubMed search | [3] | [4] |
---|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|