FILIP1

Protein-coding gene in the species Homo sapiens
FILIP1
Identifiers
AliasesFILIP1, FILIP, filamin A interacting protein 1
External IDsOMIM: 607307; MGI: 1917848; HomoloGene: 6700; GeneCards: FILIP1; OMA:FILIP1 - orthologs
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for FILIP1
Genomic location for FILIP1
Band6q14.1Start75,291,859 bp[1]
End75,493,800 bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for FILIP1
Genomic location for FILIP1
Band9|9 E1Start79,712,376 bp[2]
End79,920,133 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • myocardium of left ventricle

  • cardiac muscle tissue of right atrium

  • tibialis anterior muscle

  • deltoid muscle

  • right ventricle

  • Skeletal muscle tissue of rectus abdominis

  • biceps brachii

  • quadriceps femoris muscle

  • vastus lateralis muscle

  • Skeletal muscle tissue of biceps brachii
Top expressed in
  • interventricular septum

  • muscle of thigh

  • sciatic nerve

  • ascending aorta

  • left ventricle

  • iris

  • aortic valve

  • otolith organ

  • utricle

  • myocardium of ventricle
More reference expression data
BioGPS
n/a
Orthologs
SpeciesHumanMouse
Entrez

27145

70598

Ensembl

ENSG00000118407

ENSMUSG00000034898

UniProt

Q7Z7B0

Q9CS72

RefSeq (mRNA)

NM_001289987
NM_001300866
NM_015687

NM_001081243
NM_001357352
NM_001357353
NM_001357354

RefSeq (protein)

NP_001276916
NP_001287795
NP_056502

n/a

Location (UCSC)Chr 6: 75.29 – 75.49 MbChr 9: 79.71 – 79.92 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Filamin-A-interacting protein 1, abbreviated as FILIP1, is a protein that in humans is encoded by the FILIP1 gene.[5][6]


Interactions

FILIP1 has been shown to interact with Filamin.[7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000118407 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034898 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Nagase T, Ishikawa K, Kikuno R, Hirosawa M, Nomura N, Ohara O (Jan 2000). "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (5): 337–45. doi:10.1093/dnares/6.5.337. PMID 10574462.
  6. ^ "Entrez Gene: FILIP1 filamin A interacting protein 1".
  7. ^ Nagano, Takashi; Yoneda Takunari; Hatanaka Yumiko; Kubota Chikara; Murakami Fujio; Sato Makoto (Jul 2002). "Filamin A-interacting protein (FILIP) regulates cortical cell migration out of the ventricular zone". Nat. Cell Biol. 4 (7). England: 495–501. doi:10.1038/ncb808. ISSN 1465-7392. PMID 12055638. S2CID 4795393.

Further reading

  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Nagano T, Yoneda T, Hatanaka Y, et al. (2002). "Filamin A-interacting protein (FILIP) regulates cortical cell migration out of the ventricular zone". Nat. Cell Biol. 4 (7): 495–501. doi:10.1038/ncb808. PMID 12055638. S2CID 4795393.
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.


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