FBXO6 |
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Identifiers |
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Aliases | FBXO6, FBG2, FBS2, FBX6, Fbx6b, F-box protein 6 |
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External IDs | OMIM: 605647; MGI: 1354743; HomoloGene: 9274; GeneCards: FBXO6; OMA:FBXO6 - orthologs |
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Gene location (Human) |
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![Chromosome 1 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Ideogram_human_chromosome_1.svg/300px-Ideogram_human_chromosome_1.svg.png) | Chr. | Chromosome 1 (human)[1] |
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| Band | 1p36.22 | Start | 11,664,200 bp[1] |
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End | 11,674,354 bp[1] |
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Gene location (Mouse) |
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![Chromosome 4 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/9/9c/Ideogram_house_mouse_chromosome_4.svg/260px-Ideogram_house_mouse_chromosome_4.svg.png) | Chr. | Chromosome 4 (mouse)[2] |
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| Band | 4 E2|4 78.67 cM | Start | 148,230,173 bp[2] |
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End | 148,236,597 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - granulocyte
- monocyte
- muscle of thigh
- gastrocnemius muscle
- bronchial epithelial cell
- blood
- right lobe of liver
- olfactory zone of nasal mucosa
- mucosa of ileum
- right adrenal gland
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| Top expressed in | - urinary bladder
- muscle of thigh
- adrenal gland
- muscle tissue
- skeletal muscle tissue
- quadriceps femoris muscle
- placenta
- white adipose tissue
- lip
- right kidney
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - ubiquitin protein ligase activity
- carbohydrate binding
- ubiquitin-protein transferase activity
- protein binding
| Cellular component | - cytoplasm
- SCF ubiquitin ligase complex
- endoplasmic reticulum quality control compartment
- cytosol
| Biological process | - cellular response to DNA damage stimulus
- DNA damage checkpoint signaling
- SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
- response to unfolded protein
- DNA repair
- protein ubiquitination
- proteolysis
- ubiquitin-dependent ERAD pathway
- glycoprotein catabolic process
- protein polyubiquitination
- post-translational protein modification
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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NM_001163704 NM_001163705 NM_001163706 NM_001163707 NM_015797 |
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RefSeq (protein) | | |
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NP_001157176 NP_001157177 NP_001157178 NP_001157179 NP_056612 |
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Location (UCSC) | Chr 1: 11.66 – 11.67 Mb | Chr 4: 148.23 – 148.24 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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