DMTN |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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1QZP, 1ZV6 |
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Identifiers |
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Aliases | DMTN, DMT, EPB49, dematin actin binding protein |
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External IDs | OMIM: 125305; MGI: 99670; HomoloGene: 1496; GeneCards: DMTN; OMA:DMTN - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 8 (human)[1] |
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| Band | 8p21.3 | Start | 22,048,995 bp[1] |
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End | 22,082,527 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 14 (mouse)[2] |
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| Band | 14 D2|14 36.32 cM | Start | 70,601,263 bp[2] |
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End | 70,636,048 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - right frontal lobe
- cingulate gyrus
- anterior cingulate cortex
- prefrontal cortex
- Brodmann area 10
- nucleus accumbens
- amygdala
- Brodmann area 9
- caudate nucleus
- right hemisphere of cerebellum
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| Top expressed in | - primary visual cortex
- superior frontal gyrus
- dentate gyrus of hippocampal formation granule cell
- fetal liver hematopoietic progenitor cell
- entorhinal cortex
- perirhinal cortex
- primary motor cortex
- prefrontal cortex
- olfactory tubercle
- CA3 field
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - spectrin binding
- protein binding
- actin binding
- signaling receptor binding
- protein self-association
- actin filament binding
| Cellular component | - cytoplasm
- cytosol
- cell projection
- membrane
- cortical cytoskeleton
- plasma membrane
- platelet dense tubular network membrane
- cell projection membrane
- actin filament
- actin cytoskeleton
- spectrin-associated cytoskeleton
- perinuclear region of cytoplasm
- endomembrane system
- cytoskeleton
- postsynaptic density
- cytoplasmic vesicle
| Biological process | - negative regulation of cell-substrate adhesion
- regulation of lamellipodium assembly
- cellular response to calcium ion
- regulation of filopodium assembly
- actin filament reorganization
- regulation of actin cytoskeleton organization
- negative regulation of peptidyl-threonine phosphorylation
- positive regulation of wound healing
- actin filament bundle assembly
- positive regulation of substrate adhesion-dependent cell spreading
- negative regulation of protein targeting to membrane
- negative regulation of peptidyl-tyrosine phosphorylation
- positive regulation of blood coagulation
- calcium-mediated signaling using extracellular calcium source
- cytoskeleton organization
- actin filament capping
- transmembrane transport
- negative regulation of peptidyl-serine phosphorylation
- positive regulation of integrin-mediated signaling pathway
- protein secretion by platelet
- negative regulation of substrate adhesion-dependent cell spreading
- calcium-mediated signaling using intracellular calcium source
- positive regulation of fibroblast migration
- negative regulation of focal adhesion assembly
- actin cytoskeleton organization
- positive regulation of platelet aggregation
- cellular response to cAMP
- erythrocyte development
- regulation of cell shape
- protein-containing complex assembly
- lamellipodium assembly
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001114135 NM_001114136 NM_001114137 NM_001114138 NM_001114139
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NM_001302816 NM_001302817 NM_001978 NM_001323378 NM_001323380 NM_001323381 NM_001323382 NM_001323383 NM_001323384 NM_001323385 NM_001323387 NM_001323388 NM_001323389 NM_001323390 NM_001323391 NM_001323392 NM_001323393 NM_001323394 NM_001323395 NM_001323396 NM_001323397 NM_001323398 NM_001323399 NM_001323400 NM_001323401 NM_001323379 NM_001387723 NM_001387726 NM_001387727 NM_001387728 NM_001387730 NM_001387732 NM_001387734 NM_001387735 NM_001387736 NM_001387737 NM_001387742 NM_001387743 NM_001387744 NM_001387745 NM_001387750 NM_001387751 NM_001387752 NM_001387753 NM_001387754 NM_001387755 NM_001387756 NM_001387757 |
| NM_001252662 NM_001252663 NM_001252664 NM_001252665 NM_001252666
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NM_013514 NM_001360024 NM_001360025 NM_001360026 NM_001360027 NM_001360028 NM_001360029 NM_001360030 |
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RefSeq (protein) | NP_001107607 NP_001107608 NP_001107609 NP_001107610 NP_001107611
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NP_001289745 NP_001289746 NP_001310307 NP_001310308 NP_001310309 NP_001310310 NP_001310311 NP_001310312 NP_001310313 NP_001310314 NP_001310316 NP_001310317 NP_001310318 NP_001310319 NP_001310320 NP_001310321 NP_001310322 NP_001310323 NP_001310324 NP_001310325 NP_001310326 NP_001310327 NP_001310328 NP_001310329 NP_001310330 NP_001969 |
| NP_001239591 NP_001239592 NP_001239593 NP_001239594 NP_001239595
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NP_038542 NP_001346953 NP_001346954 NP_001346955 NP_001346956 NP_001346957 NP_001346958 NP_001346959 |
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Location (UCSC) | Chr 8: 22.05 – 22.08 Mb | Chr 14: 70.6 – 70.64 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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