DERL2 |
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Identifiers |
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Aliases | DERL2, F-LAN-1, F-LANa, FLANa, CGI-101, DERtrin-2, derlin 2, derlin-2 |
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External IDs | OMIM: 610304; MGI: 2151483; HomoloGene: 9356; GeneCards: DERL2; OMA:DERL2 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 17 (human)[1] |
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| Band | 17p13.2 | Start | 5,471,254 bp[1] |
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End | 5,486,811 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 11 (mouse)[2] |
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| Band | 11 B4|11 43.21 cM | Start | 70,897,990 bp[2] |
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End | 70,910,667 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - right testis
- left testis
- body of pancreas
- Achilles tendon
- right lobe of liver
- parotid gland
- mucosa of transverse colon
- olfactory zone of nasal mucosa
- right adrenal gland
- granulocyte
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| Top expressed in | - cumulus cell
- left lobe of liver
- seminal vesicula
- lacrimal gland
- decidua
- right lung lobe
- stroma of bone marrow
- islet of Langerhans
- right kidney
- yolk sac
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - protein binding
- serine-type endopeptidase activity
| Cellular component | - integral component of membrane
- integral component of endoplasmic reticulum membrane
- late endosome
- early endosome
- endoplasmic reticulum membrane
- endoplasmic reticulum
- membrane
- endoplasmic reticulum quality control compartment
- signal recognition particle receptor complex
- signal recognition particle
| Biological process | - endoplasmic reticulum unfolded protein response
- positive regulation of cell growth
- retrograde protein transport, ER to cytosol
- response to unfolded protein
- negative regulation of retrograde protein transport, ER to cytosol
- positive regulation of cell population proliferation
- ubiquitin-dependent ERAD pathway
- suckling behavior
- endoplasmic reticulum mannose trimming
- proteolysis
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001304777 NM_001304779 NM_016041 |
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NM_001291146 NM_001291147 NM_001291148 NM_033562 |
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RefSeq (protein) | |
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NP_001291706 NP_001291708 NP_057125 |
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NP_001278075 NP_001278076 NP_001278077 NP_291040 |
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Location (UCSC) | Chr 17: 5.47 – 5.49 Mb | Chr 11: 70.9 – 70.91 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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