DENND1A |
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Identifiers |
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Aliases | DENND1A, FAM31A, KIAA1608, DENN domain containing 1A |
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External IDs | OMIM: 613633; MGI: 2442794; HomoloGene: 17141; GeneCards: DENND1A; OMA:DENND1A - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 9 (human)[1] |
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| Band | 9q33.3 | Start | 123,379,654 bp[1] |
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End | 123,930,152 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 2 (mouse)[2] |
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| Band | 2|2 B | Start | 37,689,003 bp[2] |
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End | 38,177,402 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - monocyte
- bone marrow cells
- ventricular zone
- mucosa of ileum
- granulocyte
- right frontal lobe
- cingulate gyrus
- anterior cingulate cortex
- prefrontal cortex
- blood
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| Top expressed in | - neural layer of retina
- zygote
- primary visual cortex
- dentate gyrus of hippocampal formation granule cell
- superior frontal gyrus
- secondary oocyte
- muscle of thigh
- right kidney
- spermatocyte
- spermatid
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - guanyl-nucleotide exchange factor activity
- SH3 domain binding
- lipid binding
- phosphatidylinositol phosphate binding
- phosphatidylinositol-3-phosphate binding
| Cellular component | - membrane
- plasma membrane
- synapse
- cell junction
- neuronal cell body
- dendrite
- clathrin-coated vesicle membrane
- presynaptic membrane
- cytoplasmic vesicle
- clathrin-coated vesicle
- nucleoplasm
- cytosol
- intracellular membrane-bounded organelle
| Biological process | - endocytosis
- regulation of Rab protein signal transduction
- synaptic vesicle endocytosis
- protein transport
- positive regulation of GTPase activity
- endocytic recycling
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_020946 NM_024820 NM_001352964 NM_001352965 NM_001352966
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NM_001352967 NM_001352968 NM_001393654 NM_001400446 NM_001400449 |
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NM_146122 NM_001362973 NM_001362977 NM_001362978 |
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RefSeq (protein) | NP_065997 NP_079096 NP_001339893 NP_001339894 NP_001339895
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NP_001339896 NP_001339897 |
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NP_666234 NP_001349902 NP_001349906 NP_001349907 |
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Location (UCSC) | Chr 9: 123.38 – 123.93 Mb | Chr 2: 37.69 – 38.18 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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