CCDC88A |
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Identifiers |
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Aliases | CCDC88A, APE, GIRDIN, GIV, GRDN, HkRP1, KIAA1212, coiled-coil domain containing 88A, PEHO, PEHOL |
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External IDs | OMIM: 609736; MGI: 1925177; HomoloGene: 41180; GeneCards: CCDC88A; OMA:CCDC88A - orthologs |
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Gene location (Human) |
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![Chromosome 2 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Ideogram_human_chromosome_2.svg/300px-Ideogram_human_chromosome_2.svg.png) | Chr. | Chromosome 2 (human)[1] |
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| Band | 2p16.1 | Start | 55,287,842 bp[1] |
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End | 55,419,895 bp[1] |
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Gene location (Mouse) |
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![Chromosome 11 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/a/a5/Ideogram_house_mouse_chromosome_11.svg/260px-Ideogram_house_mouse_chromosome_11.svg.png) | Chr. | Chromosome 11 (mouse)[2] |
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| Band | 11|11 A3.3 | Start | 29,323,658 bp[2] |
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End | 29,460,808 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - internal globus pallidus
- corpus callosum
- ventricular zone
- ganglionic eminence
- Achilles tendon
- subthalamic nucleus
- buccal mucosa cell
- inferior ganglion of vagus nerve
- tendon of biceps brachii
- testicle
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| Top expressed in | - Rostral migratory stream
- barrel cortex
- tail of embryo
- genital tubercle
- lateral septal nucleus
- lateral geniculate nucleus
- mammillary body
- ventromedial nucleus
- spermatid
- anterior amygdaloid area
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/b/b6/PBB_GE_KIAA1212_221078_s_at_fs.png/250px-PBB_GE_KIAA1212_221078_s_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/e/ee/PBB_GE_KIAA1212_219387_at_fs.png/250px-PBB_GE_KIAA1212_219387_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - protein homodimerization activity
- phosphatidylinositol binding
- actin binding
- microtubule binding
- protein kinase B binding
- dynein light intermediate chain binding
- G-protein gamma-subunit binding
| Cellular component | - cytoplasm
- Golgi apparatus
- cell projection
- endoplasmic reticulum
- lamellipodium
- membrane
- cytoplasmic vesicle
- cytosol
- plasma membrane
- cell leading edge
- centrosome
- centriole
- cytoskeleton
- ciliary basal body
- COPI-coated Golgi to ER transport vesicle
| Biological process | - regulation of actin cytoskeleton organization
- nervous system development
- DNA replication
- membrane organization
- cell migration
- lamellipodium assembly
- activation of protein kinase B activity
- regulation of DNA replication
- TOR signaling
- regulation of protein phosphorylation
- regulation of cell population proliferation
- regulation of neuron projection development
- cell projection organization
- cytoskeleton-dependent intracellular transport
- cytoplasmic microtubule organization
- positive regulation of cilium assembly
- positive regulation of protein localization to cilium
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001135597 NM_001254943 NM_018084 NM_001365480 |
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NM_176841 NM_001363368 NM_001363369 |
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RefSeq (protein) | |
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NP_001129069 NP_001241872 NP_060554 NP_001352409 |
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NP_789811 NP_001350297 NP_001350298 |
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Location (UCSC) | Chr 2: 55.29 – 55.42 Mb | Chr 11: 29.32 – 29.46 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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