ACER1 |
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Identifiers |
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Aliases | ACER1, ALKCDase1, ASAH3, alkaline ceramidase 1 |
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External IDs | OMIM: 613491; MGI: 2181962; HomoloGene: 15853; GeneCards: ACER1; OMA:ACER1 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 19 (human)[1] |
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| Band | 19p13.3 | Start | 6,306,142 bp[1] |
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End | 6,333,612 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 17 (mouse)[2] |
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| Band | 17|17 D | Start | 57,260,490 bp[2] |
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End | 57,289,126 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - skin of leg
- skin of abdomen
- skin of thigh
- vulva
- human penis
- nipple
- oral cavity
- vagina
- lymph node
- ectocervix
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| Top expressed in | - skin of external ear
- lip
- condyle
- skin of back
- epithelium of stomach
- left colon
- epidermis
- skin of abdomen
- Paneth cell
- hair follicle
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - dihydroceramidase activity
- hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
- hydrolase activity
- N-acylsphingosine amidohydrolase activity
- ceramidase activity
- metal ion binding
| Cellular component | - membrane
- integral component of membrane
- endoplasmic reticulum membrane
- endoplasmic reticulum
| Biological process | - cellular response to calcium ion
- regulation of lipid metabolic process
- cell differentiation
- sphingosine biosynthetic process
- sphingolipid biosynthetic process
- response to alkaline pH
- keratinocyte differentiation
- ceramide metabolic process
- epidermis development
- lipid metabolism
- ceramide catabolic process
- sphingolipid metabolic process
- regulation of water loss via skin
- sebaceous gland development
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 19: 6.31 – 6.33 Mb | Chr 17: 57.26 – 57.29 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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