Transforming growth factor, beta 2 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/b/b2/Protein_TGFB2_PDB_1tfg.png/250px-Protein_TGFB2_PDB_1tfg.png) |
التراكيب المتوفرة | بنك بيانات البروتين | بحث أورثولوغ: PDBe, RCSB | قائمة رموز معرفات بنك بيانات البروتين | 1TFG, 2TGI, 4KXZ | | |
المعرفات |
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الرمز، (أو الرموز) | TGFB2; LDS4; TGF-beta2 |
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معرفات خارجية | OMIM: 190220 MGI: 98726 هومولوجين: 2432 بطاقات الجينات: TGFB2 Gene |
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علم الوجود الجيني | الوظيفة الجزيئية | • beta-amyloid binding • receptor signaling protein serine/threonine kinase activity • receptor binding • type II transforming growth factor beta receptor binding • cytokine activity • transforming growth factor beta receptor binding • protein binding • growth factor activity • type III transforming growth factor beta receptor binding • protein homodimerization activity • protein heterodimerization activity
| المكونات الخلوية | • extracellular region • extracellular space • endosome • axon • extracellular matrix • platelet alpha granule lumen • neuronal cell body
| العملية الإحيائية | • cell morphogenesis • cartilage condensation • angiogenesis • eye development • response to hypoxia • epithelial to mesenchymal transition • hair follicle development • blood vessel remodeling • platelet degranulation • heart morphogenesis • heart valve morphogenesis • protein phosphorylation • cell cycle arrest • transforming growth factor beta receptor signaling pathway • SMAD protein import into nucleus • cell-cell signaling • axon guidance • salivary gland morphogenesis • heart development • blood coagulation • cell death • cell proliferation • positive regulation of cell proliferation • negative regulation of cell proliferation • glial cell migration • response to wounding • embryo development • cardioblast differentiation • positive regulation of gene expression • positive regulation of epithelial cell migration • negative regulation of alkaline phosphatase activity • positive regulation of epithelial to mesenchymal transition • positive regulation of pathway-restricted SMAD protein phosphorylation • negative regulation of macrophage cytokine production • positive regulation of phosphatidylinositol 3-kinase signaling • cell growth • cell migration • signal transduction by protein phosphorylation • hemopoiesis • platelet activation • extracellular matrix organization • collagen fibril organization • positive regulation of cell growth • negative regulation of cell growth • neutrophil chemotaxis • hair follicle morphogenesis • activation of protein kinase activity • response to progesterone • positive regulation of stress-activated MAPK cascade • regulation of transforming growth factor beta2 production • positive regulation of cell adhesion mediated by integrin • wound healing • dopamine biosynthetic process • odontogenesis • response to drug • catagen • uterine wall breakdown • positive regulation of neuron apoptotic process • cell-cell junction organization • positive regulation of integrin biosynthetic process • positive regulation of ossification • positive regulation of cell cycle • positive regulation of heart contraction • somatic stem cell division • cell development • embryonic digestive tract development • neuron fate commitment • neuron development • generation of neurons • negative regulation of epithelial cell proliferation • positive regulation of protein secretion • negative regulation of immune response • positive regulation of immune response • positive regulation of cell division • positive regulation of catagen • positive regulation of cardioblast differentiation • cardiac muscle cell proliferation • cardiac epithelial to mesenchymal transition • face morphogenesis • pathway-restricted SMAD protein phosphorylation • SMAD protein signal transduction • negative regulation of cartilage development • positive regulation of activation-induced cell death of T cells • extrinsic apoptotic signaling pathway • regulation of extracellular matrix organization • regulation of complement-dependent cytotoxicity • positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
| المصادر: Amigo / QuickGO | |
نمط التعبير عن الحمض النووي الريبوزي |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/6/6b/PBB_GE_TGFB2_209908_s_at_tn.png/250px-PBB_GE_TGFB2_209908_s_at_tn.png) |
![](//upload.wikimedia.org/wikipedia/commons/thumb/0/0b/PBB_GE_TGFB2_209909_s_at_tn.png/250px-PBB_GE_TGFB2_209909_s_at_tn.png) |
![](//upload.wikimedia.org/wikipedia/commons/thumb/d/dc/PBB_GE_TGFB2_220407_s_at_tn.png/250px-PBB_GE_TGFB2_220407_s_at_tn.png) |
مصادر أخرى عن بيانات أنماط التعبير |
التقويمات |
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الأنواع | الإنسان | الفأر |
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أنتريه | 7042 | 21808 |
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انسمبل | ENSG00000092969 | ENSMUSG00000039239 |
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يونيبروت | P61812 | P27090 |
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قاعدة بيانات مرجعية (مرسال ر.ن.ا) | NM_001135599 | NM_009367 |
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قاعدة بيانات مرجعية (بروتين) | NP_001129071 | NP_033393 |
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الموقع (قاعدة بيانات UCSC) | Chr 1: 218.35 – 218.44 Mb | Chr 1: 186.62 – 186.71 Mb |
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بحث ببمد | [1] | [2] |
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